Żywe materiały

Zespół badawczy nr 2

Żywe materiały

Kierownik zespołu

dr hab. Jan Paczesny, prof. instytutu

Tematyka badawcza

Główną ideą, która jest klamrą spinającą działania grupy, jest stworzenie połączenia między biologią i chemią materiałową. Połączenie takie można zrealizować na co najmniej dwa sposoby: 1) poprzez wykorzystanie zdobyczy ewolucji (biomolekuł, wirusów, całych organizmów) do przygotowania funkcjonalnych materiałów lub 2) zastosowanie wiedzy z zakresu chemii fizycznej, materiałowej oraz nanotechnologii do tworzenia nowoczesnych nanomateriałów, które można wykorzystać w biologii i medycynie. 

Członkowie

  • dr. Jan Paczesny, Associate Professor - Team Leader
  • dr. Aleksandra Ferenc-Mrozek - Research Group Coordinator 
  • dr. Konrad Giżyński
  • dr. Hossein Maleki Ghaleh
  • dr. Bartłomiej Bończak 
  • Rafał Zbonikowski, PhD Student
  • Bartosz Kamiński, PhD Student
  • Enkhlin Ochirbat, PhD Student
  • Gunjan Tiwari, PhD Student
  • Sada Raza, PhD Student
  • Natalia Szczepańska, PhD Student 

Badania

Combining precise measurements (physical chemistry) and applying them to biochemistry and molecular biology problems might result in a major improvement of understanding of important scientific issues, which are not available for only chemists, only physicist nor only biologists. The variety and functionality of biological materials is almost impossible to be mimicked in artificial systems. Therefore, utilization of sensitivity and diversity of biomolecules and primitive organisms might result in spectacular properties of novel bio-materials. Moreover, biomolecules are usually monodisperse, even despite high molecular mass. Therefore, equations and laws established for pure systems are applicable also for bio-systems. One of the aims of the research is to learn how to take the best parts from biology, biochemistry, physical chemistry and nanotechnology and combine them together. This might be done by incorporation of biocomponents into nanotechnology or by utilization of nanotechnology and materials chemistry in the services of biology and medicine. We aim to combine both approaches and build a true “bridge” – a two way connection between the fields.

Publikacje

2024

Maleki-Ghaleh Hossein; Kamiński Bartosz; Moradpur-Tari Ehsan; Raza Sada; Khanmohammadi Mehdi; Zbonikowski Rafał; Shakeri Mohammad Sadegh; Siadati M. Hossein; Akbari-Fakhrabadi Ali; Paczesny Jan , Visible Light-Sensitive Sustainable Quantum Dot Crystals of Co/Mg Doped Natural Hydroxyapatite Possessing Antimicrobial Activity and Biocompatibility , SMALL , 2024, 20, 52

Hossein Maleki-Ghaleh Ehsan Moradpur-Tari Mohammad Shakiba Ehsan Ghasali Ziba Dargahi Danial Norouzi Arator Yashar Behnamian Ali Fallah Ali Zarrabi Ermia Aghaie Pariya Yardani Sefidi Mir Ghasem Hosseini Ali Akbari-Fakhrabadi Hamid Omidvar M Hossein Siadati , Highly efficient magnesium ferrite/graphene nano-heterostructure for visible-light photocatalytic applications: Experimental and first-principles DFT studies , Sustainable Materials and Technologies , 2024, 42, e01159

Baghchesaraee Kahila; Ghasali Ehsan; Raza Saleem; Babenko Andrii; Paimard Giti; Bashir Tariq; Maleki-Ghaleh Hossein; Jie Li; Orooji Yasin , Recent advancements in MXenes synthesis, properties, and cutting-edge applications: A comprehensive review , JOURNAL OF ENVIRONMENTAL CHEMICAL ENGINEERING , 2024, 12, 5, 113546

Saharkhiz Saber; Mostafavi Mehrnaz; Birashk Amin; Karimian Shiva; Khalilollah Shayan; Jaferian Sohrab; Yazdani Yalda; Alipourfard Iraj; Huh Yun Suk; Farani Marzieh Ramezani; Akhavan-Sigari Reza , The State-of-the-Art Overview to Application of Deep Learning in Accurate Protein Design and Structure Prediction , TOPICS IN CURRENT CHEMISTRY , 2024, 382, 3, 23

Ramezani Farani Marzieh; Lak Mandana; C. Cho William; Kang Haneul; Azarian Maryam; Yazdian Fatemeh; Harirchi Sharareh; Khoshmaram Keyvan; Alipourfard Iraj; Hushmandi Kiavash; Hwang Seung-Kyu; Huh Yun Suk , Carbon nanomaterials: a promising avenue in colorectal cancer treatment , CARBON LETTERS , 2024, 34, 8, 2035- 2053

Maleki-Ghaleh Hossein; Moradpur-Tari Ehsan; Shakiba Mohammad; Paczesny Jan; Hurley Paul K.; Siadati M. Hossein; Ansari Lida; Gity Farzan , Electronic structure of rare-earth erbium-doped platinum diselenide: A density functional theory study , JOURNAL OF PHYSICS AND CHEMISTRY OF SOLIDS , 2024, 190, 112004

Habibi Zhilvan; Karimizadeh Karvan; Nosratpour Arez; Alipourfard Iraj , Enhanced QRS detection and ECG compression using adaptive thresholding: A real-time approach for improved monitoring and diagnosis , COMPUTERS & ELECTRICAL ENGINEERING , 2024, 119, 109528

Dargahi Ziba; Ahmadi-Arpanah Anis; Moradpur-Tari Ehsan; Yarahmadi Mohadeseh; Kavanlouei Majid; Maleki-Ghaleh Hossein; Arator Danial Norouzi; Mehr Masoud Emami; Shakeri Mohammad Sadegh; Paczesny Jan; Siadati M. Hossein , Synthesis and characterization of zinc-doped hematite nanoparticles for photocatalytic applications and their electronic structure studies by density functional theory , OPTICAL MATERIALS , 2024, 157, 116234

Kamiński Bartosz; Paczesny Jan , Bacteriophage Challenges in Industrial Processes: A Historical Unveiling and Future Outlook , PATHOGENS , 2024, 13, 2, 152

Barjesteh Fereshteh; Heidari-Kalvani Nafiseh; Alipourfard Iraj; Najafi Mohammad; Bahreini Elham , Testosterone, β-estradiol, and hepatocellular carcinoma: stimulation or inhibition? A comparative effect analysis on cell cycle, apoptosis, and Wnt signaling of HepG2 cells , NAUNYN-SCHMIEDEBERGS ARCHIVES OF PHARMACOLOGY , 2024, 397, 8, 6121- 6133

Heidari-Kalvani Nafiseh; Alizadeh-Fanalou Shahin; Yarahmadi Sahar; Fallah Sudabeh; Alipourfard Iraj; Farahmandian Navid; Barjesteh Fereshteh; Bahreini Elham , Investigation of the effects of catharanthine and Q10 on Nrf2 and its association with MMP-9, MRP1, and Bcl-2 and apoptosis in a model of hepatocellular carcinoma , NAUNYN-SCHMIEDEBERGS ARCHIVES OF PHARMACOLOGY , 2024, 397, 4, 2507- 2522

Gholami Farnoosh; Seyedalipour Bagher; Heidari-Kalvani Nafiseh; Nabi-Afjadi Mohsen; Yaghoubzad-Maleki Mohammad; Fathi Zeinab; Alipourfard Iraj; Barjesteh Fereshte; Bahreini Elham , Catharanthine, an anticancer vinca alkaloid: an in silico and in vitro analysis of the autophagic system as the major mechanism of cell death in liver HepG2 cells , NAUNYN-SCHMIEDEBERGS ARCHIVES OF PHARMACOLOGY , 2024, 397, 11, 8879- 8892

Hariri Maryam; Alivirdiloo Vahid; Ardabili Nastaran Safavi; Gholami Sarah; Masoumi Sajjad; Mehraban Mohammad Reza; Alem Mahsa; Hosseini Reza Shah; Mobed Ahmad; Ghazi Farhood; Alipourfard Iraj , Biosensor-Based Nanodiagnosis of Carcinoembryonic Antigen (CEA): an Approach to Classification and Precise Detection of Cancer Biomarker , BIONANOSCIENCE , 2024, 14, 1, 185- 197

Karimi Farshid; Nejati Babak; Rahimi Fatemeh; Alivirdiloo Vahid; Alipourfard Iraj; Aghighi Ali; Raji-Amirhasani Alireza; Eslami Majid; Babaeizad Ali; Ghazi Farhood; Amandi Akram Firouzi; Dadashpour Mehdi , A State-of-the-Art Review on the Recent Advances of Mesenchymal Stem Cell Therapeutic Application in Systematic Lupus Erythematosus , IMMUNOLOGICAL INVESTIGATIONS , 2024, 53

Atamas N. O.; Yablochkova K. S.; Matushko I. P.; Lazarenko M. M. , Liquids clathrate formation and the diffusion model for aromatics hydrocarbons in ionic liquids , FLUID PHASE EQUILIBRIA , 2024, 576, 113951

Basmenj Esmaeil Roohparvar; Izadkhah Habib; Hosseinpour Maryam; Saburi Ehsan; Ezabadi Marjan Abhaji; Alipourfard Iraj , A novel approach to design a multiepitope peptide as a vaccine candidate for Bordetella pertussis , JOURNAL OF BIOMOLECULAR STRUCTURE & DYNAMICS , 2024, 42, 24, 13738- 13750

Shekarchi Ali Akbar; Hosseini Leila; Kamrani Amin; Alipourfard Iraj; Soltani-Zangbar Mohammad Sadegh; Akbari Morteza; Roshangar Leila; Aghebati-Maleki Leili; Chakari-Khiavi Forough; Chakari-Khiavi Aref; Motlagh Asghari Kimia; Danaii Shahla; Pourlak Tannaz; Ahmadian Heris Javad; Yousefi Mehdi , Evaluation of changes in exhausted T lymphocytes and miRNAs expression in the different trimesters of pregnancy in pregnant women , MOLECULAR BIOLOGY REPORTS , 2024, 51, 1, 442

Taheripak Gholamreza; Sabeti Niusha; Najar Naba; Razavi Zahrasadat; Saharkhiz Saber; Alipourfard Iraj , SIRT1 activation attenuates palmitate induced apoptosis in C2C12 muscle cells , MOLECULAR BIOLOGY REPORTS , 2024, 51, 1, 354

Niewczas Michał; Stasiewicz Karol A.; Przybysz Natalia; Pakula Anna; Paczesny Jan; Zbonikowski Rafał; Dziaduszek Jerzy; Kula Przemysław; Jaroszewicz Leszek R. , Technology and research on the influence of liquid crystal cladding doped with magnetic Fe3O4 nanoparticles on light propagation in an optical taper sensor , ADVANCED OPTICAL TECHNOLOGIES , 2024, 13, 1422695

Nematollahi Zeinab; Karimian Shiva; Taghavirashidizadeh Ali; Darvishi Mohammad; Pakmehr Seyedabbas; Erfan Amin; Teimoury Mohammad Javad; Mansouri Neda; Alipourfard Iraj , Hub genes, key miRNAs and interaction analyses in type 2 diabetes mellitus: an integrative in silico approach , INTEGRATIVE BIOLOGY , 2024, 16, zyae002

Atamas N.; Raza Sada; Paczesny Jan; Karpińska Aneta; Yablochkova K. S.; Lazarenko M. M. , Competition between indigo carmine and water in the formation of dynamics behavior at different temperatures , DYES AND PIGMENTS , 2024, 226, 112146

Hołyst Robert; Żuk Paweł J.; Maciołek Anna; Makuch Karol; Giżyński Konrad , Direction of Spontaneous Processes in Non-Equilibrium Systems with Movable/Permeable Internal Walls , ENTROPY , 2024, 26, 8, 713

Kusior Anna; Mazurkow Julia; Jelen Piotr; Bik Maciej; Raza Sada; Wdowiak Mateusz; Nikiforov Kostyantyn; Paczesny Jan , Copper Oxide Electrochemical Deposition to Create Antiviral and Antibacterial Nanocoatings , LANGMUIR , 2024, 40, 29, 14838- 14846

2023

Zbonikowski, Rafal; Iwan, Michalina; Paczesny, Jan

Stimuli-Responsive Langmuir Films Composed of Nanoparticles Decorated with Poly(N-isopropyl acrylamide) (PNIPAM) at the Air/Water Interface

ACS OMEGA 2023  8, 26

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Zbonikowski, Rafal; Mente, Pumza; Bonczak, Bartlomiej; Paczesny, Jan

Adaptive 2D and Pseudo-2D Systems: Molecular, Polymeric, and Colloidal Building Blocks for Tailored Complexity

NANOMATERIALS 2023  13, 5, 855

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Wdowiak, Mateusz; Mierzejewski, Patryk A.; Zbonikowski, Rafal; Bonczak, Bartlomiej; Paczesny, Jan

Congo red protects bacteriophages against UV irradiation and allows for the simultaneous use of phages and UV for membrane sterilization

ENVIRONMENTAL SCIENCE-WATER RESEARCH & TECHNOLOGY 2023  9, 3, 696-706

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“Makuch, Karol, Holyst, Robert, Gizynski, Konrad,  Maciolek, Anna, Zuk, Pawel J"

Steady-state thermodynamics of a system with heat and mass flow coupling     

JOURNAL OF CHEMICAL PHYSICS 2023  159 (19), 194113

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Raza, Sada; Grotek, Mateusz; Adamkiewicz, Witold; Nikiforow, Kostiantyn; Mente, Pumza; Paczesny, Jan

Enhancing the antimicrobial activity of silver nanoparticles against ESKAPE bacteria and emerging fungal pathogens by using tea extracts

NANOSCALE ADVANCES 2023  5, 21, 5786-5798

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Lyczek, Jan; Bonczak, Bartlomiej; Krzyminska, Izabela; Gizynski, Konrad; Paczesny, Jan

Gold-oxoborate nanocomposite-coated orthodontic brackets gain antibacterial properties while remaining safe for eukaryotic cells

JOURNAL OF BIOMEDICAL MATERIALS RESEARCH PART B-APPLIED BIOMATERIALS  2023 111, 5, 996-1004

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Chavan, Rohit D.; Bonczak, Bartlomiej; Kruszynska, Joanna; Mahapatra, Apurba; Ans, Muhammad; Nawrocki, Jan; Nikiforow, Kostiantyn; Yadav, Pankaj; Paczesny, Jan; Sadegh, Faranak; Unal, Muhittin; Akin, Seckin; Prochowicz, Daniel

Molecular Engineering of Azahomofullerene-based Electron Transporting Materials for Efficient and Stable Perovskite Solar Cells

CHEMISTRY OF MATERIALS  2023 35, 19, 8309-8320

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O'Connor, Ryan; Matsoso, Joyce B.; Mashindi, Victor; Mente, Pumza; Macheli, Lebohang; Moreno, Beatriz D.; Doyle, Bryan P.; Coville, Neil J.; Barrett, Dean H.

Catalyst Design: Counter Anion Effect on Ni Nanocatalysts Anchored on Hollow Carbon Sphere

NANOMATERIALS 2023 13, 3, 426

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Holyst, Robert; Makuch, Karol; Gizynski, Konrad; Maciolek, Anna; Zuk, Pawel J.

Fundamental Relation for Gas of Interacting Particles in a Heat Flow

ENTROPY 2023  25, 9, 1295

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Holyst, Robert; Zuk, Pawel J.; Makuch, Karol; Maciolek, Anna; Gizynski, Konrad

Fundamental Relation for the Ideal Gas in the Gravitational Field and Heat Flow

ENTROPY 2023 25, 11, 1483

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Celikkin, Nehar; Presutti, Dario; Maiullari, Fabio; Volpi, Marina; Promovych, Yurii; Gizynski, Konrad; Dolinska, Joanna; Wisniewska, Agnieszka; Opallo, Marcin; Paradiso, Alessia; Rinoldi, Chiara; Fuoco, Claudia; Swieszkowski, Wojciech; Bearzi, Claudia; Rizzi, Roberto; Gargioli, Cesare; Costantini, Marco

Combining rotary wet-spinning biofabrication and electro-mechanical stimulation for the in vitro production of functional myo-substitutes

BIOFABRICATION  2023  15, 4, 45012

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Maciolek, Anna; Holyst, Robert; Makuch, Karol; Gizynski, Konrad; Zuk, Pawel J.; Martyushev, Leonid M.

Parameters of State in the Global Thermodynamics of Binary Ideal Gas Mixtures in a Stationary Heat Flow          

ENTROPY 2023 25, 11, -1505

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Atamas, N. O.; Yablochkova, K. S.; Gavryushenko, D. A.; Lazarenko, M. M.

Structure and Dynamic Inhomogeneity of Liquids on the Liquid-Gas Coexistence Curve Near the Triple Point

JOURNAL OF PHASE EQUILIBRIA AND DIFFUSION  2023 44, 6, 704-713

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Ochirbat, Enkhlin; Zbonikowski, Rafal; Sulicka, Anna; Bonczak, Bartlomiej; Bonarowska, Magdalena; Los, Marcin; Malinowska, Elzbieta; Holyst, Robert; Paczesny, Jan

Heteroaggregation of virions and microplastics reduces the number of active bacteriophages in aqueous environments               

JOURNAL OF ENVIRONMENTAL QUALITY 2023 52, 3, 665-677

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Sada Raza, Mateusz Wdowiak, Jan Paczesny

An Overview of Diverse Strategies To Inactivate Enterobacteriaceae-Targeting Bacteriophages

EcoSal Plus 2023 11, 1

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N. O. Atamas, K. S. Yablochkova, M. M. Lazarenko  G. Taranyik         

Relaxation, temporal diffusion, and polarity of aromatic hydrocarbons in ionic liquid

APPLIED NANOSCIENCE 2023 13, 5101–5113

2022

Auksorius, E., Borycki, D., Wegrzyn, P., Žičkienė, I., Adomavičius, K., Sikorski, B. L., & Wojtkowski, M.
Multimode fiber as a tool to reduce cross talk in Fourier-domain full-field optical coherence tomography.
Optics Letters, https://doi.org/10.1364/OL.449498

Bończak, B. B., & Fiałkowski, M.
Donor–Acceptor Stenhouse Adducts for Stimuli-Responsive Self-Assembly of Gold Nanoparticles into Semiconducting Thin Films.
The Journal of Physical Chemistry C,  https://doi.org/10.1021/ACS.JPCC.2C00084

Paczesny, J., Wdowiak, M., & Ochirbat, E.
Bacteriophage-Based Biosensors: Detection of Bacteria and Beyond.
Nanotechnology for Infectious Diseases,  https://doi.org/10.1007/978-981-16-9190-4_20

Szuwarzyński, M., Mazur, Ł., Borkowski, M., Maćkosz, K., Giżyński, K., & Mazur, T.
Enhanced Assembly of Ag Nanoparticles for Surface-Independent Fabrication of Conductive Patterns.
ACS Applied Nano Materials, https://doi.org/10.1021/ACSANM.2C02559

Rozynek, Z., Harkavyi, Y., & Giżyński, K.
Fabrication of 1D particle structures outside a liquid environment using electric and capillary interactions: From fundamentals to applications.
Materials & Design,  https://doi.org/10.1016/J.MATDES.2022.111233

Dlamini, M. C., Dlamini, M. L., Mente, P., Tlhaole, B., Erasmus, R., Maubane-Nkadimeng, M. S., & Moma, J. A.
Photocatalytic abatement of phenol on amorphous TiO2-BiOBr-bentonite heterostructures under visible light irradiation.
Journal of Industrial and Engineering Chemistry, https://doi.org/https://doi.org/10.1016/j.jiec.2022.04.023

Stasiewicz, K. A., Jakubowska, I., Moś, J. E., Marć, P., Paczesny, J., Zbonikowski, R., & Jaroszewicz, L. R.
Optical Properties of a Tapered Optical Fiber Coated with Alkanes Doped with Fe3O4 Nanoparticles.
Sensors, https://doi.org/10.3390/s22207801

Atamas, N. O., Yablochkova, K. S., Lazarenko, M. M., & Taranyik, G.
Relaxation, temporal diffusion, and polarity of aromatic hydrocarbons in ionic liquid.
Applied Nanoscience, https://doi.org/10.1007/S13204-022-02696-Z

Łyczek, J., Bończak, B., Krzymińska, I., Giżyński, K., & Paczesny, J.
Gold–oxoborate nanocomposite-coated orthodontic brackets gain antibacterial properties while remaining safe for eukaryotic cells.
Journal of Biomedical Materials Research Part B: Applied Biomaterials, https://doi.org/10.1002/JBM.B.35208

2021

Wdowiak, M., Ochirbat, E., & Paczesny, J.
Gold—Polyoxoborates Nanocomposite Prohibits Adsorption of Bacteriophages on Inner Surfaces of Polypropylene Labware and Protects Samples from Bacterial and Yeast Infections.
Viruses, https://doi.org/10.3390/V13071206

Paczesny, J.
The use of probes and bacteriophages for bacteria detection.
In V. Gurtler (Ed.), Fluorescent Probes (1st ed.). Academic Press. https://www.elsevier.com/books/fluorescent-probes/gurtler/978-0-12-823515-7

Richter, Ł., Księżarczyk, K., Paszkowska, K., Janczuk-Richter, M., Niedziółka-Jönsson, J., Gapiński, J., Łoś, M., Hołyst, R., & Paczesny, J.
Adsorption of bacteriophages on polypropylene labware affects the reproducibility of phage research.
Scientific Reports, https://doi.org/10.1038/s41598-021-86571-x

Paczesny, J., Wolska-Pietkiewicz, M., Binkiewicz, I., & Janczuk-Richter, M.
Langmuir and Langmuir Blodgett films of zinc oxide (ZnO) nanocrystals coated with polyhedral oligomeric silsesquioxanes (POSS).
Journal of Colloid and Interface Science, https://doi.org/10.1016/j.jcis.2021.05.085

Kuczynska, K., Bończak, B., Rárová, L., Kvasnicová, M., Strnad, M., Pakulski, Z., Cmoch, P., & Fiałkowski, M.
Synthesis and cytotoxic activity of 1,2,3-triazoles derived from 2,3-seco-dihydrobetulin via a click chemistry approach.
Journal of Molecular Structure,  https://doi.org/10.1016/J.MOLSTRUC.2021.131751

Richter, Ł., Paszkowska, K., Cendrowska, U., Olgiati, F., Silva, P., Gasbarri, M., Guven, P., Paczesny, J., & Stellacci, F.
Broad-spectrum nanoparticles against bacteriophage infections.
Nanoscale, https://doi.org/10.1039/D1NR04936D

Gizynski, K., Makuch, K., Paczesny, J., Zhang, Y., Maciołek, A., & Holyst, R.
Internal energy in compressible Poiseuille flow.
Physical Review E,  https://doi.org/10.1103/PhysRevE.104.055107

Finansowanie

National Science Centre, grant

SONATA 15 UMO-2019/35/D/ST5/03613 (kierownik dr K. Giżyński) 2020 - 2023

OPUS 18 UMO-2019/35/B/ST5/03229 (kierownik dr J. Paczesny) 2020 - 2023

SONATA BIS UMO-2017/26/E/ST4/00041 (kierownik dr J. Paczesny) 2018 - 2022