Fizykochemia miękkiej materii
Kierownik zespołu
prof. dr hab. Robert Hołyst
Tematyka badawcza
Analizujemy reakcje biochemiczne na poziomie pojedynczych molekuł stosując metody spektroskopowe ze zliczaniem pojedynczych fotonów. Badamy reakcje biochemiczne w probówce i w żywych komórkach. Oprócz tego rozwijamy nowe metody nierównowagowej fizyki statystycznej. Tworzymy również podłoża do SERSa.
Członkowie
- Prof. Robert Hołyst - Team Leader
- Patrycja Kuźma, Research Group Coordinator & Lab Manager
- Prof. Anna Maciołek
- Prof. Piotr Garstecki
- Prof. Andrzej Poniewierski
- Dr. Karina Kwapiszewska
- Dr. Tomasz Kalwarczyk
- Dr. Grzegorz Bubak
- Dr. Tomasz Andryszewski
- Dr. Karol Makuch
- Dr. Paweł Żuk
- Dr. Jeffrey Everts
- Dr. Marta Pilz
- Dr. Patrycja Haniewicz
- Dr. Nima Farahmand Bafi
- Dr. Ewelina Kalwarczyk
- Dr. Ali Ebrahimi Pure
- Dr. Ladislav Derzsi
- Paweł Albrycht, SERSitive
- Aneta Magiera, PhD Student
- Alicja Zgorzelska, PhD Student
- Karolina Kucharska, PhD Student
- Sakshi Sareen, PhD Student
- Adam Kowalski, PhD Student
- Katarzyna Ulewicz, PhD Student
- Jarosław Michalski, PhD Student
- Huma Jamil, PhD Student
- Uladzislau Sakalouski, PhD Student
- Antoni Lis, PhD Student
- Tomasz Piros, PhD Student
- Tadeusz Rymarz, PhD Student
- Michał Przerwa, PhD Student
- Jakub Wróbel, Student
- Daniel Czerniejewski, Student
- Paulina Obara, Student
- Tymon Obrębski, Student
- Jan Pyrzanowski, Student
- Natalia Hołyst, Student
- Ewelina Jałonicka, Student
Publikacje
2021
Richter, Ł., Księżarczyk, K., Paszkowska, K., Janczuk-Richter, M., Niedziółka-Jönsson, J., Gapiński, J., Łoś, M., Hołyst, R., & Paczesny, J.
Adsorption of bacteriophages on polypropylene labware affects the reproducibility of phage research.
Scientific Reports, https://doi.org/10.1038/s41598-021-86571-x
Everts, J. C., & Ravnik, M.
Ionically Charged Topological Defects in Nematic Fluids.
Physical Review X, https://doi.org/10.1103/PhysRevX.11.011054
Agasty, A., Wisniewska, A., Kalwarczyk, T., Koynov, K., & Holyst, R.
Macroscopic Viscosity of Polymer Solutions from the Nanoscale Analysis.
ACS Appl. Polym. Mater., https://doi.org/10.1021/acsapm.1c00348
Kucharska, K., Pilz, M., Bielec, K., Kalwarczyk, T., Kuźma, P., & Hołyst, R.
Two Intercalation Mechanisms of Oxazole Yellow Dimer (YOYO-1) into DNA.
Molecules, https://doi.org/10.3390/molecules26123748
Kleczewska, N., Sikorski, P. J., Warminska, Z., Markiewicz, L., Kasprzyk, R., Baran, N., Kwapiszewska, K., Karpinska, A., Michalski, J., Holyst, R., Kowalska, J., & Jemielity, J.
Cellular delivery of dinucleotides by conjugation with small molecules: targeting translation initiation for anticancer applications.
Chemical Science, https://doi.org/10.1039/D1SC02143E
Al-Otaibi, J. S., Albrycht, P., Mary, Y. S., Mary, Y. S., & Księżopolska-Gocalska, M.
Concentration-dependent SERS profile of olanzapine on silver and silver-gold metallic substrates.
Chemical Papers, https://doi.org/10.1007/S11696-021-01783-9
Kalwarczyk, T., Bielec, K., Burdzy, K., & Holyst, R.
Influence of molecular rebindings on the reaction rate of complex formation.
Physical Chemistry Chemical Physics, https://doi.org/10.1039/D1CP02820K
Al-Otaibi, J. S., Albrycht, P., Mary, Y. S., Mary, Y. S., & Księżopolska-Gocalska, M.
Concentration-dependent SERS profile of olanzapine on silver and silver-gold metallic substrates.
Chemical Papers, https://doi.org/10.1007/S11696-021-01783-9
Albrycht, P., Al-Otaibi, J. S., Mary, Y. S., Mary, Y. S., Trivedi, R., & Chakraborty, B.
Surface enhanced Raman scattering investigation of pioglitazone on silver and silver-gold metal substrates – Experimental analysis and theoretical modeling.
Journal of Molecular Structure, https://doi.org/10.1016/J.MOLSTRUC.2021.130992
Richter, Ł., Paszkowska, K., Cendrowska, U., Olgiati, F., Silva, P., Gasbarri, M., Guven, P., Paczesny, J., & Stellacci, F.
Broad-spectrum nanoparticles against bacteriophage infections.
Nanoscale, https://doi.org/10.1039/D1NR04936D
Aneta Karpińska, Marta Pilz, Joanna Buczkowska, J. Żuk, P., Karolina Kucharska, Gaweł Magiera, Karina Kwapiszewska, & Robert Hołyst
Quantitative analysis of biochemical processes in living cells at a single-molecule level: a case of olaparib–PARP1 (DNA repair protein) interactions.
Analyst, https://doi.org/10.1039/D1AN01769A
Stumpf, B. H., Nowakowski, P., Eggeling, C., Maciołek, A., & Smith, A.-S.
Protein induced lipid demixing in homogeneous membranes.
Physical Review Research, https://doi.org/10.1103/PhysRevResearch.3.L042013
Gizynski, K., Makuch, K., Paczesny, J., Zhang, Y., Maciołek, A., & Holyst, R.
Internal energy in compressible Poiseuille flow.
Physical Review E, https://doi.org/10.1103/PhysRevE.104.055107
2022
Bielec, K., Kowalski, A., Bubak, G., Witkowska Nery, E., & Hołyst, R.
Ion Complexation Explains Orders of Magnitude Changes in the Equilibrium Constant of Biochemical Reactions in Buffers Crowded by Nonionic Compounds.
The Journal of Physical Chemistry Letters, https://doi.org/10.1021/ACS.JPCLETT.1C03596
Araki, T., Gomez-Solano, J. R., & Maciołek, A.
Relaxation to steady states of a binary liquid mixture around an optically heated colloid.
Physical Review E, https://doi.org/10.1103/PhysRevE.105.014123
Khan, F., Jaoui, M., Rudziński, K., Kwapiszewska, K., Martinez-Romero, A., Gil-Casanova, D., Lewandowski, M., Kleindienst, T. E., Offenberg, J. H., Krug, J. D., Surratt, J. D., & Szmigielski, R.
Cytotoxicity and oxidative stress induced by atmospheric mono-nitrophenols in human lung cells.
Environmental Pollution, https://doi.org/10.1016/J.ENVPOL.2022.119010
Żuk, P. J., Makuch, K., Hołyst, R., & Maciołek, A. Transient dynamics in the outflow of energy from a system in a nonequilibrium stationary state.
Physical Review E, https://doi.org/10.1103/PhysRevE.105.054133
Żuk, P. J.
A brief introduction to contemporary electrokinetics.
Contemporary Physics, https://doi.org/10.1080/00107514.2022.2072565
Karpińska, A., Zgorzelska, A., Kwapiszewska, K., & Hołyst, R.
Entanglement of polymer chains in hypertonic medium enhances the delivery of DNA and other biomacromolecules into cells.
Journal of Colloid and Interface Science, https://doi.org/10.1016/J.JCIS.2022.07.040
Yasmeen, N., Karpinska, A., Kalecki, J., Kutner, W., Kwapiszewska, K., & Sharma, P. S.
Electrochemically Synthesized Polyacrylamide Gel and Core–Shell Nanoparticles for 3D Cell Culture Formation.
ACS Applied Materials & Interfaces, https://doi.org/10.1021/ACSAMI.2C04904
Pacocha, N., Zapotoczna, M., Makuch, K., Boguslawski, J., & Garstecki, P.
You will know by its tail: a method for quantification of heterogeneity of bacterial populations using single-cell MIC profiling.
Lab on a Chip, https://doi.org/10.1039/D2LC00234E
Kowalski, A., Bielec, K., Bubak, G., Żuk, P. J., Czajkowski, M., Sashuk, V., Huck, W. T. S., Antosiewicz, J. M., & Holyst, R.
Effective screening of Coulomb repulsions in water accelerates reactions of like-charged compounds by orders of magnitude.
Nature Communications, https://doi.org/10.1038/s41467-022-34182-z
The reaction speed of like-charged compounds in water is extremely slow due to Coulomb repulsions. Here, the authors boost kinetics up to 5 million times by screening these interactions and increasing the local concentration of reactants using positively charged micelles. They show the effect of two independent systems and present a theoretical explanation.
2023
van der Linden, Marjolein N.; Everts, Jeffrey C.; van Roij, Rene; van Blaaderen, Alfons
Realization of the Brazil-nut effect in charged colloids without external driving
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
2023 120, 9, -e2213044120
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Ahmad, Farooq; Zahid, Muhammad; Jamil, Huma; Khan, Muhammad Ahmed; Atiq, Shahid; Bibi, Mubashira; Shahbaz, Kanwal; Adnan, Muhammad; Danish, Muhammad; Rasheed, Fazal; Tahseen, Hira; Shabbir, Muhammad Jamshaid; Bilal, Muhammad; Samreen, Ayesha
Advances in graphene-based electrode materials for high-performance supercapacitors: A review
JOURNAL OF ENERGY STORAGE 2023 72, , -108731
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Dao, Chau; Everts, Jeffrey C.; Ravnik, Miha; Tserkovnyak, Yaroslav
Nematronics: Reciprocal Coupling between Ionic Currents and Nematic Dynamics
PHYSICAL REVIEW LETTERS 2023 130, 16, -168102
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David Gendron, Grzegorz Bubak
Carbon Nanotubes and Graphene Materials as Xenobiotics in Living Systems: Is There a Consensus on Their Safety?
JOURNAL OF XENOBIOTICS 2023 13(4), 740-760
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Karpinska, Aneta; Magiera, Gawel; Kwapiszewska, Karina; Holyst, Robert
Cellular Uptake of Bevacizumab in Cervical and Breast Cancer Cells Revealed by Single-Molecule Spectroscopy
JOURNAL OF PHYSICAL CHEMISTRY LETTERS 2023 14, 5, 1272-1278
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Sareen, Sakshi; Wisniewska, Agnieszka; Kwapiszewska, Karina; Holyst, Robert
Comment on Fluorimetric sensing of ATP in water by an imidazolium hydrazone based sensor'' by S. Farshbaf and P. Anzenbacher Jr., Chem. Commun., 2019, 55, 1770
CHEMICAL COMMUNICATIONS 2023 59, 35, 5293-5295
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Makuch, Karol, Holyst, Robert, Gizynski, Konrad, Maciolek, Anna, Zuk, Pawel J
Steady-state thermodynamics of a system with heat and mass flow coupling
JOURNAL OF CHEMICAL PHYSICS 2023 159 (19), 194113
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Zbonikowski, Rafal; Iwan, Michalina; Paczesny, Jan
Stimuli-Responsive Langmuir Films Composed of Nanop s Decorated with Poly(N-isopropyl acrylamide) (PNIPAM) at the Air/Water Interface
ACS OMEGA 2023 8, 26, -
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Zajkowska-Pietrzak, Wiktoria; Turczynski, Jakub; Kret, Slawomir; Andryszewski, Tomasz; Suffczynski, Jan; Reszka, Anna; Stachowicz, Marcin; Wierzbicka, Aleksandra; Fronc, Krzysztof; Teisseyre, Henryk
Carbon Oxide Decomposition as a Novel Technique for Ultrahigh Quality ZnO Nanowire Crystallization
CRYSTAL GROWTH & DESIGN 2023 23, 9, 6442-6449
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Rathod, Jagannath; Moram, Sree Satya Bharati; Chandu, Byram; Albrycht, Pawel; Soma, Venugopal Rao
Single-step fabrication of hybrid germanium-gold/silver nanoentities by femtosecond laser ablation and applications in SERS-based sensing
NANOTECHNOLOGY 2023 34, 40, -405301
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Vasilyev, Oleg A.; Maciolek, Anna; Dietrich, S.
Sensitivity of the thermodynamics of two-dimensional systems towards the topological classes of their surfaces
PHYSICA A-STATISTICAL MECHANICS AND ITS APPLICATIONS 2023 624, , -128960
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Holyst, Robert; Zuk, Pawel J.; Makuch, Karol; Maciolek, Anna; Gizynski, Konrad
Fundamental Relation for the Ideal Gas in the Gravitational Field and Heat Flow
ENTROPY 2023 25, 11, -1483
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Holyst, Robert; Makuch, Karol; Gizynski, Konrad; Maciolek, Anna; Zuk, Pawel J.
Fundamental Relation for Gas of Interacting P s in a Heat Flow
ENTROPY 2023 25, 9, -1295
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Maciolek, Anna; Holyst, Robert; Makuch, Karol; Gizynski, Konrad; Zuk, Pawel J.; Martyushev, Leonid M.
Parameters of State in the Global Thermodynamics of Binary Ideal Gas Mixtures in a Stationary Heat Flow
ENTROPY 2023 25, 11, -1505
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Ochirbat, Enkhlin; Zbonikowski, Rafal; Sulicka, Anna; Bonczak, Bartlomiej; Bonarowska, Magdalena; Los, Marcin; Malinowska, Elzbieta; Holyst, Robert; Paczesny, Jan
Heteroaggregation of virions and microplastics reduces the number of active bacteriophages in aqueous environments
JOURNAL OF ENVIRONMENTAL QUALITY 2023 52, 3, 665-677
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Nowakowski, Piotr; Stumpf, Bernd Henning; Smith, Ana-Suncana; Maciolek, Anna
Demixing of homogeneous binary lipid membranes induced by protein inclusions
PHYSICAL REVIEW E 2023 107, 5, -54120