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The primary objective of the project is to develop the first Stimulated Raman Scattering (SRS) microscopic-microfluidic system for non-invasive imaging of live cells and apply it to rapid leukemia cell imaging, diagnostics, sorting and assessment of chemosensitivity in vitro. Multidisciplinary teams of experts establishing the consortium will characterize Raman spectra of leukemic cells and link them to biological features of the disease. These data will be thereafter used to design and construct, microfluidic-based diagnostic device utilizing SRS microscopy which will allow for quick and reliable differentiation between different types of leukemia cells providing clinicians with quantitative information crucial to make proper decisions during the course of the treatment. The envisaged microfluidic-SRS instrument will fill the gap in the current diagnostic methodology of leukemia, accelerate diagnostics and decrease its cost. Moreover, the developed methodology will open new areas of application in leukemia research.

We are looking for a highly motivated Experienced Researcher (R3) with background in microfluidics, microelectronics, automation, robotics, informatics, or optics. The successful candidate will join an international and multidisciplinary team and will i) develop optical imaging systems for detection of WBCs in microfluidic channel, ii) integrate the microfluidic devices with the SRS system, automatize standard operation protocol sequences such as deliver-trap-scan-release sort, iii) optimize cell sorting efficiency based on the acquired Raman signal.

• Development of optical imaging systems for detection of WBCs in microfluidic channels,
• Integration of the microfluidic devices with the SRS system, automation of standard operation protocol sequences such as deliver-trap-scan-release sort,
• Optimization of cell sorting based on the acquired Raman signal for efficiency and throughput.
• Data analysis, writing reports, patents and publications
• Advising younger team members, cooperation with researchers including communication with English-speaking colleagues

• Employment on 75 % time basis (for 10 months) with full remuneration cost (brutto-brutto) of 12 000 PLN per month financed by the Foundation for Polish Science Team-NET project No. POIR.04.04.00-00-16ED/18.
• Work in the outstanding scientific institution in the dynamic research group with members representing diverse interests and qualifications – see details on the website: http://ichf.pong.pl/en
• Possibility to collaborate with research groups engaged in the project (University of Warsaw, Medical University of Lodz, Institute of Haematology and Transfusion Medicine, Jagellonian University) and industrial partners (Electric System & Laser Technology).
• Engagement into an ambitious research program and possibility to build the academic career.
• Scientific and organizational support.
• Access to the modern research equipment.
• Possibility to participate in Erasmus +

• PhD in physics, engineering, electronics, informatics or similar
• Solid knowledge and hands-on experience with experimental microfluidic systems (ideally experience with development of microfluidic systems for biomedical or microbiological applications)
• Hands-on experience with photolithography and/or other microfabrication techniques
• Solid knowledge in Mathlab, LabView, phyton and/or similar environment
• Additional experience in one or more of the following fields is preferential: optics, optofluidics, acustofluidics, Raman Spectroscopy, microbiology, automation
• Creativity and enthusiasm measured by the quality and number of projects, internships, authorship in peer-reviewed publications and patents in which the Candidate participated and contributed
• Analytical thinking and critical problem-solving skills
• Excellent communications, organization and time management skills
• Fluent in spoken and written English
• Flexibility and ability to work in a multidisciplinary and multicultural research team
• Experience in supervision and mentoring of MSc and PhD students

Evaluation of the applications will be in 2 stages:

1. First stage: analysis of CV, ML and the other submitted documents
2. Second stage: interview (only the highest scoring candidates will be invited)