Business activities
Two innovative spin-off companies operating in the field of medical diagnostics - Curiosity Diagnostics and Scope Fluidics - have been created from the work conducted by the Institute. The latter has made a successful debut on the NewConnect market. On the basis of the works carried out in the Institute, other companies were established, the full list of which is presented in the table below.
InCellVu is developing a clinical-grade prototype device for in-vivo imaging of the human retina using a novel STOC-T method created by scientists from the International Centre for Translational Eye Research.
STOC-T is a revolutionary biological tissue imaging method based on a specific eye-safe laser illumination and ultra-fast data acquisition with subsequent complex numerical algorithm analysis. After the build, the device will be placed in leading European ophthalmic clinics for testing.
Scope Fluidics was founded in 2010 as the first spin-off from the Institute of Physical Chemistry, Polish Academy of Sciences (IPC PAS), with the aim to commercialize microfluidic technologies developed at the Institute. Already in 2010 the company focused on medical diagnostics. The company cooperates with the academia and integrates the points of view of medicine and business to develop innovative solutions with a high market potential. Scope Fluidics Group hires a varied and interdisciplinary team of specialists.
In 2012 Scope Fluidics founded Curiosity Diagnostics to create the PCR|ONE system that delivers the fastest bacterial and viral pathogen detection in the world. This fully automated procedure identifies up to 20 distinct pathogens and drug-resistant genes.
BacterOMIC technology delivers the first fully comprehensive Antibiotic Susceptibility Testing (AST) panel. It provides the solution to one of the biggest health threats in the world – antibiotic resistance.
We provide cutting-edge SERS substrates made for fast and accurate analysis for a wide range of analytical sciences such as pharmacy, forensic laboratories, border guard laboratories, medicine and many others. Our innovative technology enhances the sensitivity of widely known Raman spectroscopy, multiple times, due to its hi-tech roughened surface of silver or silver-gold nanoparticles.
SILIQUAN products are unique due to their internal structure our fluorescent nanoobjects are composed of small fluorescent cores, surrounded by a non-fluorescent silica shells with gradually differentiated thickness. This provides our customers with a series of nanoobjects having different physical diameters, yet constant fluorescent core size. Maintenance of the cores diameter size guarantees the utility of such nanoobjects in advanced microscopic techniques, such as fluorescence correlation spectroscopy.
SILIQUAN offers nanometer sized probes, having a selection of different surface coatings. We specialize in the production of both, fluorescent and non-fluorescent, silicone materials, offered in a wide range of sizes and forms (aqueous, non-aqueous solutions, solid state) to best suit the needs of our clients.
Cell-IN offers a reagent allowing the introduction of various types of macromolecules (from polymers and proteins to DNA molecules) into mammalian cells. The Cell-IN product works by disintegrating intracellular vesicles under osmotic shock. During disintegration, the probes inside the vesicles are released into the cell. Cell-IN was developed as an agent supporting this process - the nanostructure of the working solution proved to be crucial for the efficiency of introducing the cargos into the cytoplasm.
Cell-IN has been validated for a wide range of probes (dyes, polymers, proteins, nucleic acids, nanoparticles) as well as cell types (normal, cancer, epithelial, mesenchymal cells). Cell-IN allows the introduction of cargo with sizes ranging from single nanometers to more than 100 nm, which is a distinguishing feature in the market. Furthermore, the high viability (>80%) of cells treated with the Cell-IN procedure has been confirmed up to 3 days after the procedure.