International Centre for Translational Eye Research

The research in our group can be seen as a perfect interplay between physics, biology and chemistry. We are focusing on developing imaging techniques and using them in many biological and chemical systems. Uniqueness of our approach is using not only amplitude of the light, but also its phase in order to develop new, top class imaging systems. Optical Coherence Tomography is the great example of such method (see movie below of long-range OCT volume of human eye). Furthermore, we are implementing the innovative method for imaging distortion removal ― STOC (Spatio Temporal Optical Coherence manipulation), that have a potential to largely increase the quality of imaging through opaque layers, such as skin.

• Principal Investigator and Group Leader: prof. Maciej Wojtkowski, mwojtkowski@ichf.edu.pl
• Lab Coordinator: Anna Salamończyk, asalamonczyk@ichf.edu.pl

Research at the Integrated Structural Biology (ISB) Group aims to elucidate the mechanisms of vision, particularly proteins of the phototransduction pathway and the visual cycle, at an atomic and molecular level, using structural biology techniques and other complementary biophysics characterization methods. 

• Principal Investigator and Group Leader: dr Humberto Fernandes, hfernandes@ichf.edu.pl 
• Lab Coordinator: Magdalena Pieczyńska-Kovács, PhD, mpieczynska-kovacs@ichf.edu.pl

The Image-guided Devices for Ophthalmic Care (IDoc) laboratory seeks to research novel techniques and develop instrumentation to address unanswered questions in vision science and unmet needs in ophthalmology and optometry. The IDoc team members put their experience and know-how in optical engineering, imaging, biomedical physics, computing and mechatronics to work on translational eye research, by collaborating with vision scientists on one side and ophthalmologists, optometrists, and surgeons on the other.

• Principal Investigator and Group Leader: dr Andrea Curatolo, acuratolo@ichf.edu.pl 
• Lab Coordinator: Katarzyna Wybrańska, PhD, kwybranska@ichf.edu.pl

OBi Lab utilizes the latest advancements in molecular biology, genetics, and viral tracing techniques to find new viral therapies for the restoration of visual signal processing in the diseased retina. We use in vivo and in vitro electrophysiology for investigating the system of local and distant communication between the different populations of neurons responsible for visual information processing, how the disease changes the functioning of the visual system, for testing the effects of therapy. We harness new technologies and programming strategies to support our efforts in vision restoration.

• Principal Investigator and Group Leader: dr Andrzej Foik, afoik@ichf.edu.pl
• Lab Coordinator: dr Anna Posłuszny, aposluszny@ichf.edu.pl

The objective of the research at CGG is to leverage the latest single-cell multiomics methods to understand eye diseases. Research conducted at the CGG focuses on combining approaches from statistics, statistical physics, mathematics and computer science to develop new computational methods to handle the complexity of information and resolve biological processes from massive single-cell omics experiments.

• Principal Investigator and Group Leader: dr Marcin Tabaka, mtabaka@ichf.edu.pl 
• Lab Coordinator: dr Magdalena Banach-Orłowska, mbanach-orlowska@ichf.edu.pl