Functional Polymers

Research group no. 18

Functional Polymers

Group leader

dr hab. Piyush Sindhu Sharma

Research topics

1. Biomimetic materials for selective catalysis
Designing and synthesis of molecularly imprinted polymers allowing for mimicking active site of enzymes for selective electro- and photocatalysis. Development of materials for separation and sensing as well as degradation of toxins.   

                                                   
2. Nanostructured materials

  • Development of soft and hard templating procedures for nano-structuring in polymers for enhancement of active surface area.
  • Synthesis of multifunctional nanoparticles.
  • Development of functional ultrathin multilayered films via controlled polymerization for sensor applications.

Members

  • dr inż. Maciej Cieplak 
  • dr inż. Kamila Łępicka 
  • dr inż. Krzysztof Noworyta 
  • dr Joanna Piechowska 
  • mgr Monika Mierzejewska
  • mgr Dominik Korol
  • mgr Katarzyna Wielondek

Research

Designing of Biomimetic Materials

  • Molecularly imprinted polymers (MIPs) – Synthesis of polymers with molecular cavities capable of selective recognition of molecules for devising selective chemosensors.
  • Polymer films with developed surface – Deposition of micro-/nanostructured conductive polymer films for improved chemosensing, and energy storage.
  • Polymer electrocatalysts – Application of conductive polymer films as a selective electrocatalysts.

Publications

2024

Ayerdurai Viknasvarri; Lach Patrycja; Lis-Cieplak Agnieszka; Cieplak Maciej; Kutner Włodzimierz; Sharma Piyush Sindhu , An advantageous application of molecularly imprinted polymers in food processing and quality control , CRITICAL REVIEWS IN FOOD SCIENCE AND NUTRITION , 2024, 64, 11, 3407- 3440

Mazuryk Jarosław; Klepacka Katarzyna; Kutner Włodzimierz; Sharma Piyush Sindhu , Glyphosate: Impact on the microbiota-gut-brain axis and the immune-nervous system, and clinical cases of multiorgan toxicity , ECOTOXICOLOGY AND ENVIRONMENTAL SAFETY , 2024, 271, 115965

Mazuryk Jarosław; Klepacka Katarzyna; Kutner Włodzimierz; Sharma Piyush Sindhu , Glyphosate: Hepatotoxicity, Nephrotoxicity, Hemotoxicity, Carcinogenicity, and Clinical Cases of Endocrine, Reproductive, Cardiovascular, and Pulmonary System Intoxication , ACS PHARMACOLOGY & TRANSLATIONAL SCIENCE , 2024, 7, 5, 1205- 1236

Bartołd Katarzyna; Iskierko Zofia; Sharma Piyush Sindhu; Lin Hung-Yin; Kutner Włodzimierz , Idiopathic pulmonary fibrosis (IPF): Diagnostic routes using novel biomarkers , BIOMEDICAL JOURNAL , 2024, 47, 4, 100729

Bartołd Katarzyna; Iskierko Zofia; Borowicz Paweł; Noworyta Krzysztof; Nikiforow Kostiantyn; Ardasiewicz Andrzej; Sharma Piyush Sindhu; Lin Hung-Yin; Kutner Włodzimierz , An extended-gate field-effect transistor (EG-FET) signal transducing combined with epitope molecular imprinting for selective chemosensing of chosen idiopathic pulmonary fibrosis (IPF) biomarkers , ELECTROCHIMICA ACTA , 2024, 486, 144153

2023

Ayerdurai Viknasvarri; Cieplak Maciej; Kutner Włodzimierz         

Molecularly imprinted polymer-based electrochemical sensors for food contaminants determination

TRAC-TRENDS IN ANALYTICAL CHEMISTRY  2023 158 116830

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Łach Patrycja; Garcia-Cruz Alvaro; Canfarotta Francesco; Groves Alistair; Kałęcki Jakub; Korol Dominik; Borowicz Pawel; Nikiforow Kostiantyn; Cieplak Maciej; Kutner Włodzimierz; Piletsky Sergey A.; Sharma Piyush Sindhu

Electroactive molecularly imprinted polymer nanop s for selective glyphosate determination

BIOSENSORS & BIOELECTRONICS 2023   236 115381

.

Mazuryk Jarosław; Klepacka Katarzyna; Kutner Wlodzimierz; Sharma Piyush Sindhu

Glyphosate Separating and Sensing for Precision Agriculture and Environmental Protection in the Era of Smart Materials

ENVIRONMENTAL SCIENCE & TECHNOLOGY  2023  57 27 9898-9924

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Sudagar Alcina Johnson; Shao Shuai; Zolek Teresa; Maciejewska Dorota; Asztemborska Monika; Cieplak Maciej; Sharma Piyush Sindhu; D'Souza Francis; Kutner Włodzimierz; Noworyta Krzysztof R.

Improving the Selectivity of the C-C Coupled Product Electrosynthesis by Using Molecularly Imprinted Polymer-An Enhanced Route from Phenol to Biphenol           

ACS APPLIED MATERIALS & INTERFACES  2023    15 42 49595-49610

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Yasmeen Nabila; Etienne Mathieu; Sharma Piyush Sindhu; Kutner Włodzimierz

Artificial receptors for electrochemical sensing of bacteria          

CURRENT OPINION IN ELECTROCHEMISTRY  2023 39 101291

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Korol Dominik; Kisiel Anna; Cieplak Maciej; Michalska Agata; Sharma Piyush Sindhu; Maksymiuk Krzysztof

Synthesis of conducting molecularly imprinted polymer nanop s for estriol chemosensing

SENSORS AND ACTUATORS B-CHEMICAL 2023    382 133476

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Sudagar Alcina Johnson; Andrejkovicova Slavka; Rocha Fernando; Patinha Carla; Velosa Ana; da Silva Eduardo Ferreira 

Compressive strength and heavy metal adsorption of cork residue natural zeolite and low-grade metakaolin-based geopolymers

CONSTRUCTION AND BUILDING MATERIALS  2023 366 130125

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Kałęcki Jakub; Cieplak Maciej; Iskierko Zofia; Piechowska Joanna; Nogala Wojciech; D'Souza Francis; Sharma Piyush Sindhu 

Post-imprinting modification: electrochemical and scanning electrochemical microscopy studies of a semi-covalently surface imprinted polymer

JOURNAL OF MATERIALS CHEMISTRY B  2023 11 8 1659-1669

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Bian Yongjun; Pan Qichao; Zhu Yicheng; Liang Jia; Zhang Yuhan; Zhang Yaqiong; Zhang Shouyan; Qian Sihao; Geng Zhi; You Zhengwei; Cieplak Maciej; Sharma Piyush S.; Zhang Yaopeng; He Yong; Zhu Bo         

Durable conducting polymer electrodes pursue low impedance antifouling and electrochemical stress tolerance

APPLIED SURFACE SCIENCE 2023 621 156902

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Lee Mei-Hwa; Lin Cheng-Chih; Kutner Włodzimierz; Thomas James L.; Lin Chu-Yun; Iskierko Zofia; Lin Chien-Yu; Sharma Piyush S.; Lin Hung-Yin

MoS2 Nanosheet-Doped Peptide-Imprinted Polymer-Coated Electrodes for Electrochemical Determination of CRISPR/dCas9-Activated Protein Expression

ACS APPLIED NANO MATERIALS 2023 6 19 17369-17375

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Jaroslaw Mazuryk; Katarzyna Klepacka; Joanna Piechowska; Jakub Kałęcki; Ladislav Derzsi; Piotr Piotrowski; Piotr Paszke; Dorota A. Pawlak Simone Berneschi; Wlodzimierz Kutner; Piyush Sindhu Sharma

In-Capillary Photodeposition of Glyphosate-Containing Polyacrylamide Nanometer-Thick Films ACS

APPLIED POLYMER MATERIALS 2023  5 1 223–235

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M.-H. Lee Ch.-Ch. Lin, W. Kutner, J.L. Thomas, Ch.-Y., Lin, Z. Iskierko, Y.-S. Ku, Ch.-Y. Lin, P. Borowicz, P.S. Sharma, Y.-W. Lan, Ch.-H., Yang H.-Y. Lin

Peptide-imprinted conductive polymer on continuous monolayer molybdenum disulfide transferred electrodes for electrochemical sensing of Matrix Metalloproteinase-1 in lung cancer culture medium

BIOSENSORS & BIOELECTRONICS X  2023  13 100258

2022

Yasmeen, N., Kalecki, J., Borowicz, P., Kutner, W., & Sharma, P. S.
Electrochemically Initiated Synthesis of Polyacrylamide Microgels and Core-shell Particles.
ACS Applied Polymer Materials,  https://doi.org/10.1021/ACSAPM.1C01359

Bartold, K., Iskierko, Z., Borowicz, P., Noworyta, K., Lin, C.-Y., Kalecki, J., Sharma, P. S., Lin, H.-Y., & Kutner, W.
Molecularly imprinted polymer-based extended-gate field-effect transistor (EG-FET) chemosensor for selective determination of matrix metalloproteinase-1 (MMP-1) protein.
Biosensors and Bioelectronics,  https://doi.org/10.1016/J.BIOS.2022.114203

Łępicka, K., Sharma, P., Borowicz, P., Francius, G., & Walcarius, A.
Get closer to the intrinsic properties of Ni2+salen polymer semiconductors accessed by chain isolation inside silica nanochannels.
Journal of Materials Chemistry C, https://doi.org/10.1039/D2TC00976E

Jyoti, Żołek, T., Maciejewska, D., Gilant, E., Gniazdowska, E., Kutner, A., Noworyta, K. R., & Kutner, W.
Polytyramine Film-Coated Single-Walled Carbon Nanotube Electrochemical Chemosensor with Molecularly Imprinted Polymer Nanoparticles for Duloxetine-Selective Determination in Human Plasma.
ACS Sensors, https://doi.org/10.1021/ACSSENSORS.2C00124

Yasmeen, N., Karpinska, A., Kalecki, J., Kutner, W., Kwapiszewska, K., & Sharma, P. S.

Electrochemically Synthesized Polyacrylamide Gel and Core–Shell Nanoparticles for 3D Cell Culture Formation.

ACS Applied Materials & Interfaces, https://doi.org/10.1021/ACSAMI.2C04904

Mierzejewska, M., Łępicka, K., Kalecki, J., Lisowski, W., & Sharma, P. S.

Ni(OH)2-Type Nanoparticles Derived from Ni Salen Polymers: Structural Design toward Functional Materials for Improved Electrocatalytic Performance.

ACS Applied Materials & Interfaces, https://doi.org/10.1021/ACSAMI.2C06147

Jyoti, Dmitrieva, E., Żołek, T., Maciejewska, D., Rybakiewicz-Sekita, R., Kutner, W., & Noworyta, K. R.
An insight into the polymerization process of the selected carbazole derivatives - why does it not always lead to a polymer formation?
Electrochimica Acta,  https://doi.org/10.1016/J.ELECTACTA.2022.140948

Ayerdurai, V., Lach, P., Lis-Cieplak, A., Cieplak, M., Kutner, W., Sindhu Sharma, P.
An advantageous application of molecularly imprinted polymers in food processing and quality control.
Critical Reviews in Food Science and Nutrition, https://doi.org/10.1080/10408398.2022.2132208

Ayerdurai, V., Cieplak, M., & Kutner, W.
Molecularly imprinted polymer-based electrochemical sensors for food contaminants determination.
Trends in Analytical Chemistry,  https://doi.org/10.1016/J.TRAC.2022.116830

2021

Mazuryk, J., Sharma, P. S., & Kutner, W.
Molecularly imprinted polymer composites in drug delivery.
Molecularly Imprinted Polymer Composites, https://doi.org/10.1016/B978-0-12-819952-7.00014-7

Lach, P., Cieplak, M., Noworyta, K. R., Pieta, P., Lisowski, W., Kalecki, J., Chitta, R., D’Souza, F., Kutner, W., & Sharma, P. S.
Self-reporting molecularly imprinted polymer with the covalently immobilized ferrocene redox probe for selective electrochemical sensing of p-synephrine.
Sensors and Actuators B: Chemical, https://doi.org/10.1016/j.snb.2021.130276

Jyoti, Gonzato, C., Żołek, T., Maciejewska, D., Kutner, A., Merlier, F., Haupt, K., Sharma, P. S., Noworyta, K. R., & Kutner, W.

Molecularly imprinted polymer nanoparticles-based electrochemical chemosensors for selective determination of cilostazol and its pharmacologically active primary metabolite in human plasma.

Biosensors and Bioelectronics, https://doi.org/10.1016/J.BIOS.2021.113542

Yasmeen, N., Etienne, M., Sharma, P. S., El-Kirat-Chatel, S., Helú, M. B., & Kutner, W.
Molecularly imprinted polymer as a synthetic receptor mimic for capacitive impedimetric selective recognition of Escherichia coli K-12.
Analytica Chimica Acta, https://doi.org/10.1016/J.ACA.2021.339177

Ayerdurai, V., Garcia-Cruz, A., Piechowska, J., Cieplak, M., Borowicz, P., Noworyta, K. R., Spolnik, G., Danikiewicz, W., Lisowski, W., Pietrzyk-Le, A., D’Souza, F., Kutner, W., & Sharma, P. S.
Selective Impedimetric Chemosensing of Carcinogenic Heterocyclic Aromatic Amine in Pork by dsDNA-Mimicking Molecularly Imprinted Polymer Film-Coated Electrodes.
Journal of Agricultural and Food Chemistry, https://doi.org/10.1021/ACS.JAFC.1C05084

Jyoti, Rybakiewicz, R., Zolek, T., Maciejewska, D., Gilant, E., Buś-Kwaśnik, K., Kutner, A., Noworyta, K., & Kutner, W.
Cilostazol-imprinted polymer film-coated electrode as an electrochemical chemosensor for selective determination of cilostazol and its active primary metabolite.
Journal of Materials Chemistry B, https://doi.org/10.1039/D1TB02186A