Dioscuri Centre for Physics and Chemistry of Bacteria

Research group no. 15

Dioscuri Centre for Physics and Chemistry of Bacteria

Group leader

Dr Bartłomiej Wacław

Research topics

The Centre’s main objective is to better understand bacterial growth and evolution in the natural environment of pathogenic bacteria: the interior of an animal cell and animal secretions. The members of the Centre will use experimental in vitro models of infections, computer simulations and mathematical theory to create data driven, quantitative models of bacterial growth and evolution in these environments.

Research

  1. Experimental models of bacterial infections
  2. New methods for accurate, real-time, in situ measurement of bacterial growth
  3. The structure and growth dynamics of intra-cellular colonies (in vivo biofilms)
  4. Population dynamics of bacteria in complex fluids and topologies
  5. Population dynamics of intracellular bacteria during antibiotic treatment
  6. Bacterial growth on micro-patterned and dynamic surfaces

Publications

Postek, W., & Garstecki, P.
Droplet Microfluidics for High-Throughput Analysis of Antibiotic Susceptibility in Bacterial Cells and Populations.
Accounts of Chemical Research,  https://doi.org/10.1021/ACS.ACCOUNTS.1C00729

Cooperation

  • Department of Evolutionary Theory, MPI Plön, Germany 
  • The University of Edinburgh
  • Harvard University
  • The University of York

Financing

Dioscuri (2020-2025) (2) NAWA (2020-2024)

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