Offer no. 2/12

Method for the on-demand separation of paramagnetic material from droplet and the apparatus for the on-demand separation of paramagnetic material from droplet

• Summary:

  The present invention describes the method of on-demand separation of paramagnetic material from a droplet and a system for an on-demand separation of paramagnetic material from a droplet. The technique is based on the division of droplet into two droplets; one of which containing most of volume of initial droplet, nut no paramagnetic material, and another containing only paramagnetic material. The invention also describes a microfluidic system for such division of droplets.

• Inventors:
  Paweł Dębski, Piotr Garstecki, Sławomir Jakieła
• Advantages / Innovative aspects:
  • non-invasive metod of the separation of paramagnetic beads from droplets in a microfluidic system
  • separation on demand – the paramagnetic material is separated from the droplet only if necessary
  • applicable for microfluidic channels with oval and rectangular cross section, which is particularly important for lab-on-chip techniques
  • the system provides the separation of more than 99% of paramagnetic material from droplets
  • the improvement of the efficiency of the separation is due to the change of the shape of the channel, i.e. by widening its short segment
• Keywords:
  microfluidic techniques, lab-on-chip, diagnostics, paramagnetic beads
• Field:
  • Instruments - Analysis of biological materials
  • Chemistry - Biotechnology
• Usage:

  Plastics, Polymers, Analytical chemistry, Clinical research, Health Service, Measuring sensors, Chemical techniques

• State of the progress:
  stage of research
• Intellectual property rights:
  Patent in Germany

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