Institute of Physical Chemistry PAS (Soft Granular Matter and Tissue Engineering Group)
National Science Centre
Project title, type and project number
Artificial pancreatic islets: microfluidics-assisted reaggregation of endocrine cells inside hydrogel microcapsules, Opus 17 (2019/33/B/ST8/02145), 63/2021
dr Jan Guzowski
The goal of the project is to develop an artificial pancreatic islet based on reaggregation of the
dissociated pancreatic endocrine cells, mainly alpha- and beta-cells, into a functional tissue via
microencapsulation. The planned research tasks include:
(i) use microfluidics to encapsulate living cells (from murine cell-lines) inside sub-millimeter hydrogel
microcapsules, so-called ‘microbeads’, mimicking the actual cellular microenvironment and supporting cell
growth, interaction and metabolism; this task will involve a range of technological developments including the
design of the microfluidic chip adjusted to hydrogel viscosity, cell concentration, and the cross-linking protocol,
(ii) culture such generated artificial islets in physiological conditions,
(iii) monitor cell viability and functionality, in particular insulin secretion,
(iv) optimize a range of physico-chemical conditions for enhanced cell growth and function by using
microfluidics (type of hydrogel, bead size, compartmentalization, culture protocols, etc.).
Number of vacancies
Key responsibilities include
Position in the project
Full-time employment, Type of contract: temporary, Hours Per Week: 40
gross salary (total employment cost) of 10 000 PLN per month
Position starts on
Maximum planned period of contract/stipend agreement
12-month full time work contract (with possibility of extension)
Career development prospects at IPC PAS
More detailssee website
Biology, bioengineering, engineering and chemistry or related fields
Scientific profile of a candidate
Recognised Researcher (R2)
Key assessment criteria
The Commission will take into account the following criteria:
Employment will take place in accordance with the employment policy of the Institute of Physical Chemistry PAS https://ichf.edu.pl/files/csr/ipc-procedures.pdf and the provisions of the competition documentation of the National Science Center (NSC). The Commission will analyze CVs of the candidates. The top candidates will be invited for an online or in person interview. Good command of English is required. We reserve the right to contact and reply only to selected candidates
• The incomplete applications will be not considered.
• The results of the competition are made public.
• Candidates who have been issued a negative opinion by the Competition Committee or candidates not selected for employment have the right to appeal against the results of the evaluation. The appeal shall be lodged with the Director of the Institute within 7 days from the date of receipt of the appropriate information. The decision of the Director of the Institute shall be final.
• If the top candidate does not sign the contract, due to the resignation, we reserve the right to choose the second best candidate.
How to Apply: Send application directly to email@example.com;
IMPORTANT! email subject: “Recruitment no. 63/2021”
Deadline for the settlement of the competition
Archival announcement. We would like to thank all candidates for their submitted applications.