Job details

Place of work

Institute of Physical Chemistry (IPC) PAS

Funding institution

National Science Centre

Project description

Project title, type and project number

Comprehensive, multimodal profiling of chromatin states and gene expression in single cells, SONATA BIS 12, nr 2022/46/E/NZ2/00370, 1/2024

Project leader

Dr. Marcin Tabaka

Description

We seek a highly motivated and enthusiastic Postdoctoral Researcher at the Institute of Physical Chemistry, Polish Academy of Sciences. The position is part of the project entitled “Comprehensive, multimodal profiling of chromatin states and gene expression in single cells”, financed by the NCN (National Science Centre). Our laboratory at IPC PAS/ICTER provides an international and interdisciplinary research environment with close links to genomics, single-cell sequencing, molecular biology, biotechnology, and bioinformatics. The project involves multimodal (transcriptomic and epigenomic) profiling of immune systems using in-house high-throughput single-cell sequencing methods.

Details about the project:

The single-cell sequencing approaches allow researchers to uncover rare cell types, reveal the diversity of cell populations, infer the cellular trajectories, and discover their regulatory mechanisms. Recent progress in developing multimodal single-cell techniques has enabled us to study complex biological systems and processes simultaneously at multiple layers of gene regulation. Understanding how the gene expression programs are modulated over time in response of cells to stimuli or during disease progression is one of the long-standing challenges. We aim to develop new multimodal approaches to comprehensively interrogate the dynamics of gene regulatory elements, and downstream gene expression programs, using state-of-the-art chemical, biophysical, and genomic tools.

About the group: The Computational Genomics Group at IPC PAS led by dr. Marcin Tabaka leverages experimental and computational approaches in high-throughput single-cell transcriptome and epigenome profiling to address fundamental questions in biomedical research (https://tabaka-lab.org).

Job description

Number of vacancies

1

Key responsibilities include

  • Designing, executing, analyzing, and interpreting experiments including high throughput single-cell multimodal profiling
  • Assessing quality controls of Next Generation Sequencing data generated in the project
  • Optimization of protocols for multimodal analyses (RNA-seq, ATAC-seq, chromatin proteins, and histone modifications profiling) of single cells
  • Prepare and write scientific papers for leading journals
Offer

Position in the project

Post-doctoral position

Job type

Full-time employment, Type of contract: temporary, Hours Per Week: 40

Salary

Gross/gross salary (total employment cost) of 11 666 PLN per month (Total employment cost is the gross/gross amount including employer's expense. It would be the subject of taxes, social and health insurances and other legal deductions according to Polish

Position starts on

1.04.2024

Maximum planned period of contract/stipend agreement

full-time work contract, not exceeding 2028-05-03

We offer

  • full-time work contract, not exceeding 2028-05-03
  • Engagement into an ambitious research program and opportunity to build an academic career.

Career development prospects at IPC PAS

The job in the exciting interdisciplinary project. The successful candidate will be able to take advantage of all programs in the IPC PAS, including Young Scientists of IPC PAS competition and Mobility of Young Scientists of IPC PAS competition. The Institute provides an opportunity to participate in ERASMUS+ program.

More details

see website
Requirements

Scientific discipline

Biological Sciences, Medical Sciences

Scientific profile of a candidate

Recognised Researcher (R2)

Requirements

  • Ph.D. degree in Biotechnology, Biology, Genomics, Medicine or related quantitative discipline obtained not earlier than 7 years before the engagement in the project (this period might be longer due to family reasons according to NCN rules).
  • Solid knowledge and familiarity with techniques in Genomics
  • Familiarity with Next Generation Sequencing
  • Familiarity with single-cell methods in Genomics
  • Very good command of spoken and written English is required

Key assessment criteria

The Commission will take into account the following criteria and evaluate applications on a point scale:

  • Competence for specific tasks in a research project
  • Previous scientific achievements (publication record)
  • References
  • Candidate’s own initiative in research projects.
Required documents
  • scientific curriculum vitae, including a list of scientific achievements (scholarships, publications, patents, conference presentations, etc.).
  • motivation letter
  • minimum one recommendation letter
  • a scan of the PhD diploma or PhD attestation
Recruitment procedure

Employment will take place in accordance with the Employment policy of the Institute of Physical Chemistry PAS (https://ichf.edu.pl/files/csr/ipc-procedures.pdf) and the provisions of the competition documentation of the National Science Center (NSC) for the SONATA BIS 12 SONATA BIS 12 (ncn.gov.pl)

The Commission will analyze CVs of the candidates. The top candidates will be invited for an online/ on site interview (11.03.2024). Good command of English is required. We reserve the right to contact and reply only to selected candidates

• The incomplete applications will not be considered.

• The results of the competition are made public.

• Candidates who have been issued a negative opinion by the Competition Committee or candidates not selected for employment have the right to appeal against the results of the evaluation. The appeal shall be lodged with the Director of the Institute within 7 days from the date of receipt of the appropriate information. The decision of the Director of the Institute shall be final.

• The position will be awarded to the person who obtains the highest number of points. If the top candidate does not sign the contract, due to the resignation, we reserve the right to choose the second-best candidate.

Additional information

How to Apply: Send application directly to rekrutacja@ichf.edu.pl;

IMPORTANT! email subject: “Recruitment no. 1/2024” (emails without this number will not be considered)

A post-doc type post is a full-time post, scheduled by the project’s principal investigator for a person who has been conferred a PhD degree in the year of employment in the project or within 7 years before 1 January of the year of employment in the project.* This period may be extended by a time of long-term (in excess of 90 days) documented sick leaves or rehabilitation leaves granted on account of being unfit to work. In addition, the period may be extended by the number of months of a child care leave granted pursuant to the Labour Code and in the case of women, by 18 months for every child born or adopted, whichever manner of accounting for career breaks is preferable.

*For researchers with multiple PhDs, the date of the first PhD award is deemed the reference date

Deadlines

Application deadline

29.02.2024 16:00

Deadline for the settlement of the competition

15.03.2024

Send the application via the "Apply to the position" button, or to rekrutacja@ichf.edu.pl with the title 1/2024.

Apply to the position

By submitting the application, you consent to the processing of your personal data in the recruitment process. The controller of your personal data is the Institute of Physical Chemistry of the Polish Academy of Sciences with its registered office in Warsaw, NIP: 5250008755 (the "Institute"). The Institute will process your data for the purpose of carrying out scientific and research activities, providing services and contact with the Institute, on the basis of a contract (in connection with the performance of the contract or in order to take action on your request before the contract is concluded – Article 6, paragraph 1, letter b) of GDPR), the legitimate interest of the Institute (Article 6, paragraph 1, letter f) of the GDPR) and legal provisions (Article 6, paragraph 1, letter c) of the GDPR) - depending on the circumstances

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Date of announcement: 25.01.2024

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