Soft Granular Matter and Tissue Engineering

Research group no. 19

Soft Granular Matter and Tissue Engineering

Group leader

Research topics

In the group we study soft granular materials - in particular dense emulsions, foams and microhydrogels - for applications in fabrication of complex microcapsules and scaffolds for 3D cell culture. We use microfluidics to generate and control such structures. We develop new techniques of 3D printing using biomaterials, including printing of granular or porous structures, and techniques of 3D cell- and tissue culture in vitro.

Members

  • dr Michał Bogdan
  • dr Ronald Terrazas Mallea
  • dr Katarzyna Rojek
  • mgr Debjita Mukherjee
  • mgr Jonathan Pullas Navarrete
  • dr Iraj Alipourfard
  • mgr inż. Leon Jurkiewicz

Publications

2021

Idaszek, J., Volpi, M., Paradiso, A., Quoc, M. N., Górecka, Ż., Klak, M., Tymicki, G., Berman, A., Wierzbicki, M., Jaworski, S., Costantini, M., Kępczyńska, A., Chwalibóg, E. S., Wszoła, M., & Święszkowski, W.
Alginate-based tissue-specific bioinks for multi-material 3D-bioprinting of pancreatic islets and blood vessels: A step towards vascularized pancreas grafts.
Bioprinting, https://doi.org/10.1016/J.BPRINT.2021.E00163

Rinoldi, C., Zargarian, S. S., Nakielski, P., Li, X., Liguori, A., Petronella, F., Presutti, D., Wang, Q., Costantini, M., Sio, L. De, Gualandi, C., Ding, B., & Pierini, F.
Nanotechnology-Assisted RNA Delivery: From Nucleic Acid Therapeutics to COVID-19 Vaccines.
Small Methods, https://doi.org/10.1002/SMTD.202100402

Agarwal, T., Chiesa, I., Presutti, D., Irawan, V., Vajanthri, K. Y., Costantini, M., Nakagawa, Y., Tan, S. A., Makvandi, P., Zare, E. N., Sharifi, E., De Maria, C., Ikoma, T., & Maiti, T. K.
Recent advances in bioprinting technologies for engineering different cartilage-based tissues.
Materials Science and Engineering C, https://doi.org/10.1016/j.msec.2021.112005

Agarwal, T., Costantini, M., & Maiti, T. K.
Recent advances in tissue engineering and anticancer modalities with photosynthetic microorganisms as potent oxygen generators.
Biomedical Engineering Advances, 1, 100005. https://doi.org/10.1016/j.bea.2021.100005

Chirivì, M., Maiullari, F., Milan, M., Presutti, D., Cordiglieri, C., Crosti, M., Sarnicola, M. L., Soluri, A., Volpi, M., Święszkowski, W., Prati, D., Rizzi, M., Costantini, M., Seliktar, D., Parisi, C., Bearzi, C., & Rizzi, R.
Tumor Extracellular Matrix Stiffness Promptly Modulates the Phenotype and Gene Expression of Infiltrating T Lymphocytes.
International Journal of Molecular Sciences, https://doi.org/10.3390/ijms22115862

Celikkin, N., Presutti, D., Maiullari, F., Fornetti, E., Agarwal, T., Paradiso, A., Volpi, M., Święszkowski, W., Bearzi, C., Barbetta, A., Zhang, Y. S., Gargioli, C., Rizzi, R., & Costantini, M.
Tackling Current Biomedical Challenges With Frontier Biofabrication and Organ-On-A-Chip Technologies.
Frontiers in Bioengineering and Biotechnology, https://doi.org/10.3389/FBIOE.2021.732130

Agarwal, T., Costantini, M., & Maiti, T. K.
Extrusion 3D printing with Pectin-based ink formulations: Recent trends in tissue engineering and food manufacturing.
Biomedical Engineering Advances,  https://doi.org/10.1016/J.BEA.2021.100018

2022

Guzowski, J., Buda, R. J., Costantini, M., Ćwiklińska, M., Garstecki, P., & Stone, H. A.
From dynamic self-organization to avalanching instabilities in soft-granular threads.
Soft Matter, https://doi.org/10.1039/D1SM01350E

Bogdan, M., Montessori, A., Tiribocchi, A., Bonaccorso, F., Lauricella, M., Jurkiewicz, L., Succi, S., & Guzowski, J.
Stochastic Jetting and Dripping in Confined Soft Granular Flows.
Physical Review Letters,  https://doi.org/10.1103/PhysRevLett.128.128001

Lai, Y.-K., Opalski, A. S., Garstecki, P., Derzsi, L., & Guzowski, J.
A double-step emulsification device for direct generation of double emulsions.
Soft Matter. https://doi.org/10.1039/D2SM00327A

Durve, M., Tiribocchi, A., Bonaccorso, F., Montessori, A., Lauricella, M., Bogdan, M., Guzowski, J., & Succi, S.
DropTrack-Automatic droplet tracking with YOLOv5 and DeepSORT for microfluidic applications.
Phys. Fluids, https://doi.org/10.1063/5.0097597

Rojek, K. O., Ćwiklińska, M., Kuczak, J., & Guzowski, J.
Microfluidic Formulation of Topological Hydrogels for Microtissue Engineering.
Chemical Reviews, https://doi.org/10.1021/ACS.CHEMREV.1C00798

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