Plasmonic nanostructures for bio-spectroscopic analysis

Research group no. 1

Plasmonic nanostructures for bio-spectroscopic analysis

Group leader

dr hab. Agnieszka Michota-Kamińska, prof. Instytutu

Research topics

Application of spectroscopic methods (SERS, Raman, UV-Vis) for:

  • identification of pathogenic fungi from skin samples,
  • detection of pathogenic bacteria from physiological fluids, i.e. blood plasma, urine and cerebrospinal fluid,
  • detection of pathogenic bacteria from food in accordance with ISO standards,
  • direct detection and quantification of immunomarkers in body fluids, and
  • detection of cancer cells circulating in the blood, including analysis on clinical samples.

For the analysis of the obtained spectral data of complex biological systems from clinical samples and their quantitative assessment,
the numerical chemometric methods based, among others, on the analysis of the main components are applied. 

Members

  • mgr Berus Sylwia
  • mgr Czaplicka Marta
  • mgr Deskur Tomiła
  • mgr Niciński Krzysztof
  • dr inż. Nowicka Ariadna
  • dr inż. Szymborski Tomasz
  • dr Witkowska-Iwan Evelin

Publications

2021

Szymborski, T., Stepanenko, Y., Niciński, K., Piecyk, P., Berus, S. M., Adamczyk-Popławska, M., & Kamińska, A.
Ultrasensitive SERS platform made via femtosecond laser micromachining for biomedical applications.
Journal of Materials Research and Technology, https://doi.org/10.1016/j.jmrt.2021.03.083

Witkowska, E., Łasica, A. M., Niciński, K., Potempa, J., & Kamińska, A.
In Search of Spectroscopic Signatures of Periodontitis: A SERS-Based Magnetomicrofluidic Sensor for Detection of Porphyromonas gingivalis and Aggregatibacter actinomycetemcomitans.
ACS Sensors, https://doi.org/10.1021/acssensors.1c00166

Nowicka, A. B., Czaplicka, M., Szymborski, T., & Kamińska, A.
Combined negative dielectrophoresis with a flexible SERS platform as a novel strategy for rapid detection and identification of bacteria.
Analytical and Bioanalytical Chemistry, https://doi.org/10.1007/s00216-021-03169-y

Berus, S. M., Adamczyk-Popławska, M., Młynarczyk-Bonikowska, B., Witkowska, E., Szymborski, T., Waluk, J., & Kamińska, A.
SERS-based sensor for the detection of sexually transmitted pathogens in the male swab specimens: A new approach for clinical diagnosis.
Biosensors and Bioelectronics, https://doi.org/10.1016/j.bios.2021.113358

Czaplicka, M., Kowalska, A. A., Nowicka, A. B., Kurzydłowski, D., Gronkiewicz, Z., Machulak, A., Kukwa, W., & Kamińska, A.
Raman spectroscopy and surface-enhanced Raman spectroscopy (SERS) spectra of salivary glands carcinoma, tumor and healthy tissues and their homogenates analyzed by chemometry: Towards development of the novel tool for clinical diagnosis.
Analytica Chimica Acta, https://doi.org/10.1016/J.ACA.2021.338784

Kowalska, A. A., Czaplicka, M., Nowicka, A. B., Niciński, K., Piotrowska, A., & Kamińska, A.

Association between grade brain tumors and the interleukin-10 receptor subunit alpha based on surface-enhanced Raman spectroscopy and multivariate analysis.

Journal of Raman Spectroscopy, https://doi.org/10.1002/JRS.6211