Living Materials
Group leader
dr hab. Jan Paczesny, prof. instytutu
Research topics
The main idea, which unifies the research of the group, is to create a connection between biology and material chemistry. Such a connection can be accomplished in at least two ways: 1) by using natural building blocks, perfected by evolution (biomolecules, viruses, whole organisms) to prepare functional materials or 2) applying knowledge of physical chemistry, material engineering and nanotechnology to create modern nanomaterials that can be used in biology and medicine.
Members
- dr inż. Konrad Giżyński
- mgr Mateusz Wdowiak
- mgr inż. Rafał Zbonikowski
- Enkhlin Ochirbat
- dr inż. Witold Adamkiewicz
- dr Prabhjot Singh
- dr Hossein Maleki Ghaleh
- mgr Bartosz Kamiński
- mgr inż. Enkhlin Ochirbat
- mgr Gunjan Tiwari
- mgr Mateusz Wdowiak
- mgr inż. Rafał Zbonikowski
Research
Combining precise measurements (physical chemistry) and applying them to biochemistry and molecular biology problems might result in a major improvement of understanding of important scientific issues, which are not available for only chemists, only physicist nor only biologists. The variety and functionality of biological materials is almost impossible to be mimicked in artificial systems. Therefore, utilization of sensitivity and diversity of biomolecules and primitive organisms might result in spectacular properties of novel bio-materials. Moreover, biomolecules are usually monodisperse, even despite high molecular mass. Therefore, equations and laws established for pure systems are applicable also for bio-systems. One of the aims of the research is to learn how to take the best parts from biology, biochemistry, physical chemistry and nanotechnology and combine them together. This might be done by incorporation of biocomponents into nanotechnology or by utilization of nanotechnology and materials chemistry in the services of biology and medicine. We aim to combine both approaches and build a true “bridge” – a two way connection between the fields.
Publications
2021
Wdowiak, M., Ochirbat, E., & Paczesny, J.
Gold—Polyoxoborates Nanocomposite Prohibits Adsorption of Bacteriophages on Inner Surfaces of Polypropylene Labware and Protects Samples from Bacterial and Yeast Infections.
Viruses, https://doi.org/10.3390/V13071206
Paczesny, J.
The use of probes and bacteriophages for bacteria detection.
In V. Gurtler (Ed.), Fluorescent Probes (1st ed.). Academic Press. https://www.elsevier.com/books/fluorescent-probes/gurtler/978-0-12-823515-7
Richter, Ł., Księżarczyk, K., Paszkowska, K., Janczuk-Richter, M., Niedziółka-Jönsson, J., Gapiński, J., Łoś, M., Hołyst, R., & Paczesny, J.
Adsorption of bacteriophages on polypropylene labware affects the reproducibility of phage research.
Scientific Reports, https://doi.org/10.1038/s41598-021-86571-x
Paczesny, J., Wolska-Pietkiewicz, M., Binkiewicz, I., & Janczuk-Richter, M.
Langmuir and Langmuir Blodgett films of zinc oxide (ZnO) nanocrystals coated with polyhedral oligomeric silsesquioxanes (POSS).
Journal of Colloid and Interface Science, https://doi.org/10.1016/j.jcis.2021.05.08
Kuczynska, K., Bończak, B., Rárová, L., Kvasnicová, M., Strnad, M., Pakulski, Z., Cmoch, P., & Fiałkowski, M.
Synthesis and cytotoxic activity of 1,2,3-triazoles derived from 2,3-seco-dihydrobetulin via a click chemistry approach.
Journal of Molecular Structure, https://doi.org/10.1016/J.MOLSTRUC.2021.131751
Richter, Ł., Paszkowska, K., Cendrowska, U., Olgiati, F., Silva, P., Gasbarri, M., Guven, P., Paczesny, J., & Stellacci, F.
Broad-spectrum nanoparticles against bacteriophage infections.
Nanoscale, https://doi.org/10.1039/D1NR04936D
Gizynski, K., Makuch, K., Paczesny, J., Zhang, Y., Maciołek, A., & Holyst, R.
Internal energy in compressible Poiseuille flow.
Physical Review E, https://doi.org/10.1103/PhysRevE.104.055107
2022
Auksorius, E., Borycki, D., Wegrzyn, P., Žičkienė, I., Adomavičius, K., Sikorski, B. L., & Wojtkowski, M.
Multimode fiber as a tool to reduce cross talk in Fourier-domain full-field optical coherence tomography.
Optics Letters, https://doi.org/10.1364/OL.449498
Bończak, B. B., & Fiałkowski, M.
Donor–Acceptor Stenhouse Adducts for Stimuli-Responsive Self-Assembly of Gold Nanoparticles into Semiconducting Thin Films.
The Journal of Physical Chemistry C, https://doi.org/10.1021/ACS.JPCC.2C00084
Paczesny, J., Wdowiak, M., & Ochirbat, E.
Bacteriophage-Based Biosensors: Detection of Bacteria and Beyond.
Nanotechnology for Infectious Diseases, https://doi.org/10.1007/978-981-16-9190-4_20
Financing
National Science Centre, grant
SONATA 15 UMO-2019/35/D/ST5/03613 (kierownik dr K. Giżyński) 2020 - 2023
OPUS 18 UMO-2019/35/B/ST5/03229 (kierownik dr J. Paczesny) 2020 - 2023
SONATA BIS UMO-2017/26/E/ST4/00041 (kierownik dr J. Paczesny) 2018 - 2022