Functional Polymers

Research group no. 18

Functional Polymers

Group leader

dr hab. Piyush Sindhu Sharma

Research topics

1. Biomimetic materials for selective catalysis
Designing and synthesis of molecularly imprinted polymers allowing for mimicking active site of enzymes for selective electro- and photocatalysis. Development of materials for separation and sensing as well as degradation of toxins.   

                                                   
2. Nanostructured materials

  • Development of soft and hard templating procedures for nano-structuring in polymers for enhancement of active surface area.
  • Synthesis of multifunctional nanoparticles.
  • Development of functional ultrathin multilayered films via controlled polymerization for sensor applications.

Members

  • dr inż. Maciej Cieplak 
  • dr inż. Kamila Łępicka 
  • dr inż. Krzysztof Noworyta 
  • dr Joanna Piechowska 
  • mgr Monika Mierzejewska
  • mgr Dominik Korol
  • mgr Katarzyna Wielondek

Research

Designing of Biomimetic Materials

  • Molecularly imprinted polymers (MIPs) – Synthesis of polymers with molecular cavities capable of selective recognition of molecules for devising selective chemosensors.
  • Polymer films with developed surface – Deposition of micro-/nanostructured conductive polymer films for improved chemosensing, and energy storage.
  • Polymer electrocatalysts – Application of conductive polymer films as a selective electrocatalysts.

Publications

2021

Mazuryk, J., Sharma, P. S., & Kutner, W.
Molecularly imprinted polymer composites in drug delivery.
Molecularly Imprinted Polymer Composites, https://doi.org/10.1016/B978-0-12-819952-7.00014-7

Lach, P., Cieplak, M., Noworyta, K. R., Pieta, P., Lisowski, W., Kalecki, J., Chitta, R., D’Souza, F., Kutner, W., & Sharma, P. S.
Self-reporting molecularly imprinted polymer with the covalently immobilized ferrocene redox probe for selective electrochemical sensing of p-synephrine.
Sensors and Actuators B: Chemical, https://doi.org/10.1016/j.snb.2021.130276

Jyoti, Gonzato, C., Żołek, T., Maciejewska, D., Kutner, A., Merlier, F., Haupt, K., Sharma, P. S., Noworyta, K. R., & Kutner, W.

Molecularly imprinted polymer nanoparticles-based electrochemical chemosensors for selective determination of cilostazol and its pharmacologically active primary metabolite in human plasma.

Biosensors and Bioelectronics, https://doi.org/10.1016/J.BIOS.2021.113542

Yasmeen, N., Etienne, M., Sharma, P. S., El-Kirat-Chatel, S., Helú, M. B., & Kutner, W.
Molecularly imprinted polymer as a synthetic receptor mimic for capacitive impedimetric selective recognition of Escherichia coli K-12.
Analytica Chimica Acta, https://doi.org/10.1016/J.ACA.2021.339177

Ayerdurai, V., Garcia-Cruz, A., Piechowska, J., Cieplak, M., Borowicz, P., Noworyta, K. R., Spolnik, G., Danikiewicz, W., Lisowski, W., Pietrzyk-Le, A., D’Souza, F., Kutner, W., & Sharma, P. S.
Selective Impedimetric Chemosensing of Carcinogenic Heterocyclic Aromatic Amine in Pork by dsDNA-Mimicking Molecularly Imprinted Polymer Film-Coated Electrodes.
Journal of Agricultural and Food Chemistry, https://doi.org/10.1021/ACS.JAFC.1C05084

Jyoti, Rybakiewicz, R., Zolek, T., Maciejewska, D., Gilant, E., Buś-Kwaśnik, K., Kutner, A., Noworyta, K., & Kutner, W.
Cilostazol-imprinted polymer film-coated electrode as an electrochemical chemosensor for selective determination of cilostazol and its active primary metabolite.
Journal of Materials Chemistry B, https://doi.org/10.1039/D1TB02186A

2022

Yasmeen, N., Kalecki, J., Borowicz, P., Kutner, W., & Sharma, P. S.
Electrochemically Initiated Synthesis of Polyacrylamide Microgels and Core-shell Particles.
ACS Applied Polymer Materials,  https://doi.org/10.1021/ACSAPM.1C01359

Bartold, K., Iskierko, Z., Borowicz, P., Noworyta, K., Lin, C.-Y., Kalecki, J., Sharma, P. S., Lin, H.-Y., & Kutner, W.
Molecularly imprinted polymer-based extended-gate field-effect transistor (EG-FET) chemosensor for selective determination of matrix metalloproteinase-1 (MMP-1) protein.
Biosensors and Bioelectronics,  https://doi.org/10.1016/J.BIOS.2022.114203

Łępicka, K., Sharma, P., Borowicz, P., Francius, G., & Walcarius, A.
Get closer to the intrinsic properties of Ni2+salen polymer semiconductors accessed by chain isolation inside silica nanochannels.
Journal of Materials Chemistry C, https://doi.org/10.1039/D2TC00976E

Jyoti, Żołek, T., Maciejewska, D., Gilant, E., Gniazdowska, E., Kutner, A., Noworyta, K. R., & Kutner, W.
Polytyramine Film-Coated Single-Walled Carbon Nanotube Electrochemical Chemosensor with Molecularly Imprinted Polymer Nanoparticles for Duloxetine-Selective Determination in Human Plasma.
ACS Sensors, https://doi.org/10.1021/ACSSENSORS.2C00124

Yasmeen, N., Karpinska, A., Kalecki, J., Kutner, W., Kwapiszewska, K., & Sharma, P. S.

Electrochemically Synthesized Polyacrylamide Gel and Core–Shell Nanoparticles for 3D Cell Culture Formation.

ACS Applied Materials & Interfaces, https://doi.org/10.1021/ACSAMI.2C04904

Mierzejewska, M., Łępicka, K., Kalecki, J., Lisowski, W., & Sharma, P. S.

Ni(OH)2-Type Nanoparticles Derived from Ni Salen Polymers: Structural Design toward Functional Materials for Improved Electrocatalytic Performance.

ACS Applied Materials & Interfaces, https://doi.org/10.1021/ACSAMI.2C06147

Jyoti, Dmitrieva, E., Żołek, T., Maciejewska, D., Rybakiewicz-Sekita, R., Kutner, W., & Noworyta, K. R.
An insight into the polymerization process of the selected carbazole derivatives - why does it not always lead to a polymer formation?
Electrochimica Acta,  https://doi.org/10.1016/J.ELECTACTA.2022.140948

Ayerdurai, V., Lach, P., Lis-Cieplak, A., Cieplak, M., Kutner, W., Sindhu Sharma, P.
An advantageous application of molecularly imprinted polymers in food processing and quality control.
Critical Reviews in Food Science and Nutrition, https://doi.org/10.1080/10408398.2022.2132208

Ayerdurai, V., Cieplak, M., & Kutner, W.
Molecularly imprinted polymer-based electrochemical sensors for food contaminants determination.
Trends in Analytical Chemistry,  https://doi.org/10.1016/J.TRAC.2022.116830

2023

Mater, J., Chem, B., Kalecki, J., Cieplak, M., Iskierko, Z., Piechowska, J., Nogala, W., D’souza, F., & Sharma, P. S.
Post-imprinting modification: electrochemical and scanning electrochemical microscopy studies of a semi-covalently surface imprinted polymer.
Journal of Materials Chemistry B, https://doi.org/10.1039/D2TB02116A
Introduction of redox-active tracer to the imprinted molecular cavities by post-imprinting modification and its confirmation by scanning electrochemical microscopy.

Korol, D., Kisiel, A., Cieplak, M., Michalska, A., Sharma, P. S., & Maksymiuk, K.
Synthesis of conducting molecularly imprinted polymer nanoparticles for estriol chemosensing.
Sensors and Actuators B: Chemical, https://doi.org/10.1016/J.SNB.2023.133476

Bian, Y., Pan, Q., Zhu, Y., Liang, J., Zhang, Y., Zhang, Y., Zhang, S., Qian, S., Geng, Z., You, Z., Cieplak, M., Sharma, P. S., Zhang, Y., He, Y., & Zhu, B.
Durable conducting polymer electrodes pursue low impedance, antifouling, and electrochemical stress tolerance.
Applied Surface Science,  https://doi.org/10.1016/J.APSUSC.2023.156902