Dioscuri Centre for Physics and Chemistry of Bacteria

Research group no. 15

Dioscuri Centre for Physics and Chemistry of Bacteria

Group leader

Dr Bartłomiej Wacław

Research topics

The Centre’s main objective is to better understand bacterial growth and evolution in the natural environment of pathogenic bacteria: the interior of an animal cell and animal secretions. The members of the Centre will use experimental in vitro models of infections, computer simulations and mathematical theory to create data driven, quantitative models of bacterial growth and evolution in these environments.

Members

  • Dr Bartłomiej Wacław (Leader)
  • Dr Katarzyna Bartołd (Administrative Coordinator)
  • Joanna Materska (PhD student)
  • Klaudia Staśkiewicz (PhD student)
  • Patrycja Kuźma (Lab Manager)
  • Dr Elin Lilja (Postdoctoral Researcher)
  • Dr Pragyesh Dixit (Postdoctoral Researcher)
  • Dr Ilyas Djafer-Cherif (Postdoctoral Researcher)
  • Dr Karolina Drabik (Postdoctoral Researcher)
  • Dr Jarosław A. Pankowski (Postdoctoral Researcher)
  • Dr hab. Anna Ochab-Marcinek
  • Dr Łukasz Zinkiewicz
  • Dr Piotr Ciąćka
  • Dr Marek Kochańczyk

Research

  1. Experimental models of bacterial infections
  2. New methods for accurate, real-time, in situ measurement of bacterial growth
  3. The structure and growth dynamics of intra-cellular colonies (in vivo biofilms)
  4. Population dynamics of bacteria in complex fluids and topologies
  5. Population dynamics of intracellular bacteria during antibiotic treatment
  6. Bacterial growth on micro-patterned and dynamic surfaces

Publications

2024

M. Raatz A. de Azevedo-Lopes K. Drabik A. Traulsen B. Wacław , Pathogen non-planktonic phases within the urinary tract impact early infection and resistance evolution , ISME Journal , 2024, 18, 1, wrae191

Postek Witold; Staśkiewicz Klaudia; Lilja Elin; Wacław Bartłomiej , Substrate geometry affects population dynamics in a bacterial biofilm , PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA , 2024, 121, 17, e2315361121

Jimenez-Castellanos Juan-Carlos; Wacław Bartłomiej; Meynert Alison; McAteer Sean P.; Schneiders Thamarai , Rapid evolution of colistin resistance in a bioreactor model of infection of Klebsiella pneumoniae , COMMUNICATIONS BIOLOGY , 2024, 7, 1, 794

Szymczak Mateusz; Pankowski Jarosław A.; Kwiatek Agnieszka; Grygorcewicz Bartłomiej; Karczewska-Golec Joanna; Sadowska Kamila; Golec Piotr , An effective antibiofilm strategy based on bacteriophages armed with silver nanoparticles , SCIENTIFIC REPORTS , 2024, 14, 1, 9088

Giannakou M.; Wacław B. , Resonant noise amplification in a predator-prey model with quasi-discrete generations , SCIENTIFIC REPORTS , 2024, 14, 1, 16783

Blavatska Viktoria; Wacław Bartłomiej , Evolutionary adaptation is facilitated by the presence of lethal genotypes , PHYSICAL REVIEW RESEARCH , 2024, 6, 1, 13286

Blavatska Viktoria; Ilnytskyi Jaroslav; Laehderanta Erkki , Coagulation-flocculation process on a lattice: Monte Carlo simulations , JOURNAL OF PHYSICS A-MATHEMATICAL AND THEORETICAL , 2024, 57, 31, 315002

Haydukivska K.; Blavatska V. , Universal properties of branched copolymers in dilute solutions , CONDENSED MATTER PHYSICS , 2024, 27, 1, 13301

O. Pizio T. Patsahan V. Blavatska , Computer simulations of soft matter.On 60-th anniversary of Jaroslav Ilnytskyi , Condensed Matter Physics , 2024, 27,No.1,10101:1–5

2023

Hallatschek Oskar; Datta Sujit S.; Drescher Knut; Dunkel Joern; Elgeti Jens; Wacław Bartek; Wingreen Ned S.             

Proliferating active matter

NATURE REVIEWS PHYSICS 2023 5, 7, 407-419

Nalin Francesco; Tirelli Maria Celeste; Garstecki Piotr; Postek Witold; Costantini Marco          

Tuna-step: tunable parallelized step emulsification for the generation of droplets with dynamic volume control to 3D print functionally graded porous materials

LAB ON A CHIP  2023 24, 1, 113-126

Haydukivska Khristine; Blavatska Viktoria; Paturej Jarosław

The size and shape of snowflake-shaped polymers in dilute solution: Analytical and numerical approaches

JOURNAL OF MOLECULAR LIQUIDS  2023 392, 123430

Haydukivska K., Blavatska V., Paturaj J.

Molecular conformations of dumbbell-shaped polymers in good solvent

PHYSICAL REVIEW E  2023 108, 034502

Haydukivska, K.; Blavatska, V.   

On the swelling properties of pom-pom polymers: impact of backbone length

CONDENSED MATTER PHYSICS  2023  26, 2, 23301

Cooperation

  • Department of Evolutionary Theory, MPI Plön, Germany 
  • The University of Edinburgh
  • Harvard University
  • The University of York

Financing

Dioscuri (2020-2025) (2) NAWA (2020-2024)