Job details Print page

This project will develop a high throughput microfluidics-based device for the quantitative characterization of biochemical reactions using fluorescence-based methods. We intend that this improvement paves a way towards the quantitative study of biomolecule interactions in living systems and preliminary research after discovering new pharmaceuticals. Subsequently, we will use a newly developed device to quantify the stability of 20 base-pair DNA-RNA oligonucleotides with differently located multiple mismatches in various environmental conditions, such as ions concentration, pH, and temperature. As well, we will measure interactions between double-strand DNA and single-strand RNA.

We are looking for an experimentalist with strong theoretical background in chemistry to cope with the physico-chemical problems in physical chemistry. We guarantee access to top-notch instrumentation and well equipped laboratories.

1. Construction and testing of the microfluidics high-throughput devices for analysis of biochemical reaction.

2.  Analysis of RNA-DNA complex formation for strands with

mismatches.

3. Preparation of the Ph.D. thesis

We offer 5 000 PLN per month stipend to the month in which the midterm evaluation of the doctoral student at the doctoral school is carried out and 6 000 PLN thereafter subject to successful mid-term evaluation. The stipendship is for 48 months.

The successful candidate will be part of a Soft Condensed Matter Group. Funds are allocated to cover participation in international conferences and for five months fellowship at the Radboud University (Netherlands). PhD student is obliged to apply for funding for six months fellowship at the Radboud University (Netherlands) in the competition carried out by the Polish National Agency for Academic Exchange (NAWA) during his/her doctoral period at Doctoral school.

Institute provides opportunity to participate in ERASMUS + programme.

1. Education: Master degree of Chemistry or related discipline.

2. Good knowledge of English.

3. Strong motivation and commitment.

4. Knowledge of the FCS technique (Fluorescence Correlation Spectroscopy) and the basics of microfluidic techniques will be a welcome advantage.

The call is open to all those who are not PhD holders and are not students at the doctoral schools.

The Commission will take into account the following criteria:

a)competences of candidates to perform specific tasks in a research project, (70 % of the final score)

b)previous scientific achievements of candidates, including publications in the renowned publishers/scientific journals, (30 % of the final score)