Job details

Recruitment result
Place of work

Institute of Physical Chemistry PAS

Funding institution

National Science Center (NSC)

Project description

Project title, type and project number

Microfluidic methods for quantitative antibiotic susceptibility assays with single cell resolution; MAESTRO 10 Project No. 2018/30/A/ST4/00036

Project leader

prof. Piotr Garstecki


The objective of the project is to develop an analytical platform to encapsulate bacterial cells into droplets using microfluidics, incubate them and detect growth without optical labeling. In the envisioned protocol, the sample culture of cells will be serially diluted and each dilution split and mixed with multiple concentrations of antibiotic to screen inoculum density and antibiotic concentration with digital droplet assays. The assays at high and low inoculum density will allow us to count the fraction of populated droplets that produced dense colonies of bacteria. These counts will allow us to measure the single-cell Minimum Inhibitory Concentration (scMIC) level and the inoculum effect (IE) while the low-density screens will uncover the phenotypic heteroresistance, p(scMIC). The method will offer a wealth of information for research on the response of cells and bacterial colonies to antibiotics, and hopefully will guide more effective treatments regimens.

Job description

Key responsibilities include

  • Designing and implementing microbiological experiments on developed microfluidic platforms
  • Determination of the heterogeneity and hetero-resistance of the phenotype of  growing bacterial population exposed to antibiotics using genetic techniques
  • Quantitative determination of the inoculum effect
  • Data analysis, writing reports and scientific publications
  • Cooperation with researchers, including communication with English-speaking colleagues


4500 PLN

Position starts on


Maximum planned period of contract/stipend agreement

The position is for the period of 32 months (with the possibility to extend to 36 months if the project is prolonged by NCN).

We offer


  • We offer 4500 PLN per month scholarship financed by the NSC MAESTRO 10 Project No. 2018/30/A/ST4/00036. The position is for the period of 32 months (with the possibility to extend to 36 months if the project is prolonged by NCN).

Career development benefits:

  • Work in the outstanding scientific institution in the dynamic research group with members representing diverse interests and qualifications – see details on the website:
  • Pursuing PhD degree
  • Participation in international conferences and Erasmus+ projects

For additional job details: Contact



  • MSc diploma in microbiology, bioengineering, biotechnology, chemistry, physics, bioinformatics, electronic engineering, mechanical engineering, or similar
  • Creativity and enthusiasm measured by the quality and number of projects, study record, internships, authorship in peer-reviewed publications and patents in which the Candidate participated and contributed.
  • Analytical thinking and critical problem solving skills.
  • Excellent communication, organization and time management skills
  • Fluent in spoken and written English
  • Flexibility and ability to work in a multidisciplinary and multicultural research team
  • Direct experience with microfluidics as well as microbiological and molecular biology techniques is an asset

Key assessment criteria

  • The best applicants will be invited for an interview (online). The interview for „Warszawska Szkoła Doktorska Nauk Ścisłych i BioMedycznych” (Warsaw Doctoral School “Warsaw-4-PhD”) will most likely be carried out at the very beginning of February 2021.
  • The scholarship will be awarded in accordance with the NCN regulations: „Regulamin przyznawania stypendiów naukowych w projektach badawczych finansowanych ze środków narodowego centrum nauki" and in accordance with the Employment policy of the Institute of Physical Chemistry PAS ( )
  • The Commission will take into account the following criteria:
  1.  competences of candidates for specific tasks in a research project,
  2. previous scientific achievements of candidates,
  3. awards and distinctions of the candidate resulting from the conducted research.
  • The commission will evaluate applications on a point scale.
  • The results of the competition are made public.
  • The competition will be settled after the Doctoral School recruitment results are published.
  • Scheduled date of starting work within the Project: February-March 2021.
Required documents

Complete application should include the following documents:

  • scientific curriculum vitae, including a list of scientific achievements (scholarships, publications, patents, conference presentations, etc.).
  • motivation letter
  • recommendation letter
  • a transcript of the grades/credits received during the last stage of studies and grade point average
Recruitment procedure

Application Details:

  • Application Deadline: 5th of January, 2021
  • Send an application directly to; IMPORTANT: email title “Recruitment 075-2020”
  • Additionally, to be eligible, applicants are required to submit simultaneously their application to the online recruitment system of Warszawska Szkoła Doktorska Nauk Ścisłych i BioMedycznych” [Warsaw Doctoral School “Warsaw-4-PhD”] between 22nd December 2020 and 5th January 2021. Number of the project: 3.3 Quantitative, label-free and real-time monitoring of bacterial growth in nanoliter droplets
  • Required Language: English
Additional information

By submitting this application you consent to the processing of your personal data in the recruitment process.

The controller of your personal data is the Institute of Physical Chemistry of the Polish Academy of Sciences with its registered office in Warsaw, NIP: 5250008755 (the "Institute"). The Institute will process your data for the purpose of carrying out scientific and research activities, providing services and contact with the Institute, on the basis of a contract (in connection with the performance of the contract or in order to take action on your request before the contract is concluded – Article 6, paragraph 1, letter b) of GDPR), the legitimate interest of the Institute (Article 6, paragraph 1, letter f) of the GDPR) and legal provisions (Article 6, paragraph 1, letter c) of the GDPR) - depending on the circumstances.

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Application deadline

5.01.2021 0:00

Archival announcement. We would like to thank all candidates for their submitted applications.

Date of announcement: 11.12.2020

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