Job details

Recruitment result
Place of work

Institute of Physical Chemistry PAS (Microfluidics and Complex Fluids Group)

Funding institution

National Science Centre

Project description

Project title, type and project number

Microfluidic methods for quantitative antibiotic susceptibility assays with single cell resolution, MAESTRO 10 No. 2018/30/A/ST4/00036, 64/2021

Project leader

prof. Piotr Garstecki


The objective of the project is to develop an analytical platform to encapsulate bacterial cells into droplets using microfluidics, incubate them and detect growth without optical labeling. In the envisioned protocol, the sample culture of cells will be serially diluted and each dilution split and mixed with multiple concentrations of antibiotic to screen inoculum density and antibiotic concentration with digital droplet assays. The assays at high and low inoculum density will allow us to count the fraction of populated droplets that produced dense colonies of bacteria. These counts will allow us to measure the single-cell Minimum Inhibitory Concentration (scMIC) level and the inoculum effect (IE) while the low-density screens will uncover the phenotypic heteroresistance, p(scMIC). The method will offer a wealth of information for research on the response of cells and bacterial colonies to antibiotics, and hopefully will guide more effective treatments regimens.

We are looking for a highly motivated postdoctoral candidate with background in biological sciences (microbiology, bioengineering, biochemistry, biology), physics, chemistry or similar and possibly with experience in designing and fabricating microfluidic devices. 

The successful candidate will join a multinational and interdisciplinary team of scientist and will be responsible for designing, constructing and testing microfluidic systems for microbial testing of antibiotics in high-throughput and point-of-care (POC) formats.

Job description

Number of vacancies


Key responsibilities include

  • Design, construction and test droplet-based microfluidic systems for single-cell encapsulation and Antibiotic Susceptibility Testing (AST)
  • Microbial cell culturing
  • Monitoring the growth of a large number of single bacterial cells isolated in nanoliter droplets. Determination of the heterogeneity of phenotypic response of individual cells in population
  • Data analysis, writing reports and scientific publications
  • Cooperation with researchers, including communication with English-speaking colleagues
  • Support for PhD students

Position in the project


Job type

Full-time employment


10 000 PLN per month, That is the gross/gross amount including employer's expense. It would be the subject to taxes, social and health insurance and other legal deductions according to Polish law.

Position starts on


Maximum planned period of contract/stipend agreement

12-month full time work contract with the possibility of extension

We offer

  • 12-month full time work contract with the possibility of extension
  • 36 days of vacation, social security, health insurance
  • Work in the outstanding scientific institution in the dynamic research group with members representing diverse interests and qualifications – see details on the website:
  • Participation in international conferences and Erasmus projects
  • Engagement into an ambitious research program and possibility to build the academic career

Career development prospects at IPC PAS

International cooperation with experienced researchers. Work in the outstanding scientific institution in the dynamic research group with members representing diverse interests and qualifications


Scientific discipline

Biological sciences (microbiology, biotechnology, bioengineering, biochemistry, biology) chemistry, physics or related fields

Scientific profile of a candidate

Recognised Researcher (R2)


  • PhD degree in biological sciences (microbiology, biotechnology, bioengineering, biochemistry, biology) chemistry, physics or related fields
  • Experience with cell culture and standard laboratory techniques
  • Experience with AST techniques, good understanding of AMR and related issues (origin, mechanism, consequences, and challenges), overview of the available diagnostic and treatment strategies.
  • Experience with confocal microscopy
  • Experience in experimental work with microfluidic systems, especially with multiphase systems; knowledge of microfabrication techniques and characterization of microfluidic devices (soft-lithography, CAD design, profilometry, microscopic techniques) will be considered as valuable assets.

Key assessment criteria

First stage (analysis of CVs):

  • Expertise in microbiology, biochemistry, microfluidics and instrument handling related to the project (0-5 points)
  • Participation in scientific projects especially in international projects, internships, (0-2 points)
  • Scientific achievements – publications, patents, awards, grants (0-2 points)
  • Motivation and recommendation (0-1 points)

Second stage (interview):

  • Presentation of the results of previous research, experience in managing research projects, problem solving skills (0-3 points)
  • Knowledge in the field of research thematically related to the project. Strongest skills according to candidate’s own definition (0-3 points)
  • Motivation to work in the project, future plans and presentation of own research ideas (0-2 points)
  • Analytical thinking, scientific language and reporting skills (0-1 points)
  •  Communication skills and level of English. (0-1 points)
Required documents
  • scientific curriculum vitae, including a list of scientific achievements (scholarships, publications, patents, conference presentations, etc.).
  • motivation letter
  • recommendation letter
  • citation report (e.g. from Web of Science) including the number of publication, number of citation without self-citation, h-index of the Candidate
  • a scan of the PhD diploma
  • a scan of the MSc diploma
Recruitment procedure

How to Apply: Send application directly to;

 IMPORTANT: email title “Recruitment 64/2021”;

Employment will take place in accordance with the Employment policy of the Institute of Physical Chemistry PAS and the provisions of the competition documentation of the National Science Center (NSC) for the MAESTRO 10 contest  The Commission will analyze CVs of the candidates. The top candidates will be invited for an online or in person interview.

• The incomplete applications will be not considered.

• The results of the competition are made public.

• Candidates who have been issued a negative opinion by the Recruitment Committee or candidates not selected for employment have the right to appeal against the results of the evaluation. The appeal shall be lodged with the Director of the Institute within 7 days from the date of receipt of the appropriate information. The decision of the Director of the Institute shall be final.

• If the top candidate does not sign the contract due to the resignation, we reserve the right to choose the next candidate from the ranking list.

Additional information

How to Apply: Send application directly to;

IMPORTANT! email subject: “Recruitment no. 64/2021


Application deadline

23.11.2021 23:50

Deadline for the settlement of the competition


Archival announcement. We would like to thank all candidates for their submitted applications.

Date of announcement: 5.11.2021

Join us