Job details

Recruitment result
Place of work

Microfluidics and Complex Fluids Group, IPC PAS

Funding institution

Foundation for Polish Science

Project description

Project title, type and project number

RApID: Label-free and rapid optical imaging, detection and sorting of leukemia cells TEAM-NET Project No. POIR.04.04.00-00-16ED/18, 44/2021

Project leader

Prof. Czesław Radzewicz

Description

The primary objective of the project is to develop the first Stimulated Raman Scattering (SRS) microscopic-microfluidic system for non-invasive imaging of live cells and apply it to rapid leukemia cell imaging, diagnostics, sorting and assessment of chemosensitivity in vitro. Multidisciplinary teams of experts establishing the consortium will characterize Raman spectra of leukemic cells and link them to biological features of the disease. These data will be thereafter used to design and construct, microfluidic-based diagnostic device utilizing SRS microscopy which will allow for quick and reliable differentiation between different types of leukemia cells providing clinicians with quantitative information crucial to make proper decisions during the course of the treatment. The envisaged microfluidic-SRS instrument will fill the gap in the current diagnostic methodology of leukemia, accelerate diagnostics and decrease its cost. Moreover the developed methodology will open new areas of application in leukemia research.

We are looking for a highly motivated experienced researcher with strong background in synthetic chemistry, surface chemistry, emulsion science,  physical chemistry or similar; ideally also with experience in droplet-based microfluidics. The successful candidate will join a multinational and interdisciplinary team and will be responsible for synthesizing biocompatible surfactants (primarily fluoro-surfactants) for encapsulation of white blood cells and for development of surface modification techniques rendering microfluidic channels made of polycarbonate, PMMA, PDMS and glass/quartz hydrophilic and/or hydrophobic. Ideally the candidate will also support and advise younger team members in material science, surface and interface chemistry and microfabrication techniques.

Job description

Number of vacancies

1

Key responsibilities include

  • Synthesis of biocompatible surfactants (primarily fluoro-surfactants) for encapsulation of white blood cells
  • Development of surface modification techniques and establishment of surface modification protocols in microfluidic channels made of polycarbonate, PMMA, PDMS and glass/quartz
  • Data analysis, writing reports, patents and publications
  • Advising younger team members, cooperation with researchers including communication with English-speaking colleagues
Offer

Position in the project

Experienced researcher

Job type

Temporal, part-time employment contract (50% engagement)

Salary

full employment cost (brutto-brutto) of 8000 PLN per month (50 percent of time involvement)

Position starts on

1.10.2021

Maximum planned period of contract/stipend agreement

12 months

We offer

Requirements

Scientific discipline

Synthetic chemistry/surface chemistry

Scientific profile of a candidate

Established Researcher (R3)

Requirements

  • PhD degree in chemistry or related fields
  • Solid knowledge in synthetic chemistry, organic chemistry, surface chemistry, emulsion science (especially in surfactant synthesis)
  • Experience in microfluidics will be a great asset
  • Analytical thinking and critical problem solving skills
  • Fluent in spoken and written English
  • Flexibility and ability to work in a multidisciplinary and multicultural research team

Key assessment criteria

  • Knowledge in the field of research thematically related to the project
  • Past experiences and achievements
  • Academic record
  • Motivation to work in the project, ambitions and future plans
Required documents
  • Scientific Curriculum vitae including work experiences; academic record; scientific projects the candidate has participated  and his/her role in the project;  trainings, internships and scientific visits; grants and awards
  • Motivation letter including past experiences related to the position
  • Scans of diplomas (MSc, PhD)
  • List of publications and patents
  • Citation report (preferably based on Web of Science Core Collection)
Recruitment procedure
  • The evaluation will be a point-based two-step process. In the first stage of recruitment an initial assessment of the candidate's experience and achievements will be evaluated by the Recruitment Committee based on the submitted documents. In the second stage the top candidates will be invited to an interview (to be held online via skype or zoom).
  • The position will be awarded to the applicant with the highest score, i.e. with the best suited profile and most experiences with similar projects.
  • The results of the competition will be made public.
  • The competition can be cancelled without a notice.
  • Candidates who have been issued a negative opinion by the Competition Committee or candidates not selected for employment have the right to appeal against the results of the evaluation. The appeal shall be lodged with the Director of the Institute within 7 days from the date of receipt of the appropriate information
Additional information

For additional information contact: lderzsi@ichf.edu.pl, microfluidics@ichf.edu.pl

Deadlines

Application deadline

3.09.2021 23:00

Deadline for the settlement of the competition

20.09.2021

Archival announcement. We would like to thank all candidates for their submitted applications.

Date of announcement: 18.08.2021

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