Microfluidics and Complex Fluids Group, IPC PAS
Foundation for Polish Science
Project title, type and project number
RApID: Label-free and rapid optical imaging, detection and sorting of leukemia cells TEAM-NET Project No. POIR.04.04.00-00-16ED/18, 44/2021
Project leader
Prof. Czesław Radzewicz
Description
The primary objective of the project is to develop the first Stimulated Raman Scattering (SRS) microscopic-microfluidic system for non-invasive imaging of live cells and apply it to rapid leukemia cell imaging, diagnostics, sorting and assessment of chemosensitivity in vitro. Multidisciplinary teams of experts establishing the consortium will characterize Raman spectra of leukemic cells and link them to biological features of the disease. These data will be thereafter used to design and construct, microfluidic-based diagnostic device utilizing SRS microscopy which will allow for quick and reliable differentiation between different types of leukemia cells providing clinicians with quantitative information crucial to make proper decisions during the course of the treatment. The envisaged microfluidic-SRS instrument will fill the gap in the current diagnostic methodology of leukemia, accelerate diagnostics and decrease its cost. Moreover the developed methodology will open new areas of application in leukemia research.
We are looking for a highly motivated experienced researcher with strong background in synthetic chemistry, surface chemistry, emulsion science, physical chemistry or similar; ideally also with experience in droplet-based microfluidics. The successful candidate will join a multinational and interdisciplinary team and will be responsible for synthesizing biocompatible surfactants (primarily fluoro-surfactants) for encapsulation of white blood cells and for development of surface modification techniques rendering microfluidic channels made of polycarbonate, PMMA, PDMS and glass/quartz hydrophilic and/or hydrophobic. Ideally the candidate will also support and advise younger team members in material science, surface and interface chemistry and microfabrication techniques.
Number of vacancies
1
Key responsibilities include
Position in the project
Experienced researcher
Job type
Temporal, part-time employment contract (50% engagement)
Salary
full employment cost (brutto-brutto) of 8000 PLN per month (50 percent of time involvement)
Position starts on
1.10.2021
Maximum planned period of contract/stipend agreement
12 months
We offer
Scientific discipline
Synthetic chemistry/surface chemistry
Scientific profile of a candidate
Established Researcher (R3)
Requirements
Key assessment criteria
For additional information contact: lderzsi@ichf.edu.pl, microfluidics@ichf.edu.pl
Application deadline
3.09.2021 23:00
Deadline for the settlement of the competition
20.09.2021
Archival announcement. We would like to thank all candidates for their submitted applications.