"Synteza nowych molekularnych homo- i heterometalicznych jednostek budulcowych jako prekursorów materiałów typu MOF"
"Synthesis of novel molecular homo- and heterometallic building blocks as MOFs’ precursors" (project 21) – liczba miejsc 1
Leader: prof. dr hab. inż Janusz Lewiński
ICP PAS Group: Coordination complexes and functional materials
MOFs are a class of hybrid materials that have attracted considerable attention in recent years due to their intriguing structural motifs and potential applications in catalysis, adsorption, gas storage and sensing. An emerging approach in the rational assembly of MOF networks is based on application of pre-designed secondary building units (SBU) of both metal nodes and organic linkers. Recently, we have revealed “SMART’’ (SBU-based Mechanochemical Approach for pRecursor Transformation) strategy that exploited oxo-zinc clusters as preassembled molecular building blocks for the mechanochemical synthesis of isoreticular MOF.
The proposed research project we will be focused on seeking alternative inorganic strategies to the synthesis of oxo-zinc clusters. An interesting extension will be development of synthetic procedures to oxocarboxylate or oxoamidate clusters involving Co2+, Fe2+ and Ni2+ centers. Additionally, novel heterobimetallic molecular clusters, e.g. oxo-clusters of the formula [Zn4-xMx(µ4-O)(O2CR)6] (where M = Zn2+, Co2+, Fe2+ and Ni2+) will be synthesized by the combined inorganic-organometallic approach.
 (a) Lee, J.; Farha, O. K.; Roberts, J.; Scheidt, K. A.; Nguyen, S. T.; Hupp, J. T.; Chem. Soc. Rev., 2009, 38, 1450; (b) Kurmoo, M., Chem. Soc. Rev., 2009, 38, 1353; (c) Allendorf, M. D.; Bauer, C. A.; Bhakta, R. K.; Houk, R. J. T., Chem. Soc. Rev., 2009, 38, 1330; (d) Morris, R. E.; Wheatley, P. S., Angew. Chem., Int. Ed. 2008, 47, 4966; (e) Li, J.-R.; Kuppler, R. J.; Zhou, H.-C., Chem. Soc. Rev., 2009, 38, 1477; (f) C. Janiak, J. K. Vieth, New J. Chem. 2010, 34, 2366.
 O’Keeffe, M.; Yaghi, O. M., Chem. Rev. 2012, 112, 675.
 Prochowicz, D.; Sokołowski, K.; Justyniak, I.; Kornowicz, A.; Fairen-Jimenez, D.; Friščić, T.; Lewiński, J., Chem. Commun. 2015, 51, 4032; D. Prochowicz, J. Nawrocki, M. Terlecki, W. Marynowski, J. Lewiński, Inorg. Chem. 2018, 57, 13437
 Nawrocki, J; Prochowicz, D.; Justyniak, I; Leusen, J.; Kornowicz, A; Kögerler, P.; Lewiński, J., Inorg. Chem. 2019, submitted.
The main goal of the project is the synthesis of novel molecular building blocks that will be utilized as precursors of novel metallosupramolecular architectures prepared by mechanochemical as well as solution-based methods. Inherent part of this research project will be the utilization of functional ligands for the synthesis of molecular building blocks in order to introduce the desired functionality to the resulting porous material.
Requirements for applicants
- MSc degree in chemisty, physics or related science fields
- Fluency in English in writing and speech
- Basic experience in inorganic synthetic methods and characterization of materials (e.g. NMR, PXRD, IR, MS, UV-Vis)
"Czujniki pojedynczych cz±steczek oparte na DNA origami i materiałach dwuwymiarowych"
"Single-molecule sensors based on DNA origami and 2D materials" (project 22) – liczba miejsc 1.
Leader: prof. Jacek Waluk, promotor pomocniczy dr Izabela Kamińska
ICP PAS Group: Photophysics and spectroscopy of photoactive systems
When we investigate systems composed of many (thousands, millions) particles, using traditional techniques, information about individual elements is hidden behind the average values obtained for the entire system. In order to better understand complex and inhomogeneous systems, it is necessary to measure single molecules. Nonetheless, simultaneous detection and measurement of many single molecules is a big challenge. We can realize it with a help of carefully designed and fully controlled structures, which additionally should enhance the signal from single molecules. In order to construct such sensors, all its components need to be precisely organized, with controlled orientation. The next task is a placement with nanometric accuracy in a selected location, active elements of the sensor (for example DNA structure or antibody) designed to detect biomolecules. It is important to fulfill both requirements. It can be realized with DNA origami technique, which enables the fabrication of 3D DNA constructs thousands times smaller than a hair, solely from single DNA strands. DNA origami is a powerful tool, because it enables parallel fabrication of the structure and positioning of all elements, for example metallic nanoparticles, used to enhance the signal.
The main goal of the project is the detection of single viral DNA. We will fabricate sensors based on DNA origami, as well as metallic nanostructures and graphene. The precise control of the spatial arrangement of all elements allows the use of their unique properties, for example metallic nanostructures for the enhancement of the signal (fluorescence) of single molecules. This project is a contribution to very exciting fields of nanotechnology, biosensors, plasmonics or nanophotonics.
Requirements for applicants
- Enthusiasm and engagement in the scientific work.
- Motivation for independent research work.
- Knowledge in nanomaterials and graphene.
- Basic knowledge in optics, fluorescence microscopy and single-molecule studies.
- Good knowledge in English.
- Knowledge in LabView and Matlab is a plus.